关键词: 腰围, 腰围身高比, 体重指数, 青少年, 代谢紊乱, 腹型肥胖

Abstract: Objective To examine the performance of waist circumference (WC),waist-height ratio (WHtR) and body mass index (BMI) for predicting metabolic disorders in children and adolescents,and to provide scientific evidence for early warning of metabolic disorders. Methods A total of 1 170 children and adolescents aged 7~17 years from urban area of Jinan were included in this study.Receiver operating characteristic curve (ROC) analysis was used to compare the area under curves (AUCs) of WC,WHtR and BMI for predicting metabolic disorders.Logistic regression model was conducted to examine obesity defined using WC (≥age- and sex- specific P₉₀),WHtR (≥0.50) and BMI (≥age- and sex- specific obesity cut-offs) respectively,for predicting the risk of metabolic disorders. Results The area under curve value (AUC) of WC for predicting more than one or two of four metabolic disorders (including hyperglycemia,hypertension,lowered HDL-C,and elevated TG) were 0.63 (0.59~0.66) and 0.74 (0.69~0.79),respectively.The corresponding values of WHtR were 0.62 (0.58~0.65) and 0.74 (0.69~0.79),and the corresponding values of BMI were 0.64(0.60~0.67) and 0.75(0.70~0.80),respectively.The odds ratios (ORs) of abdominal obesity defined by WC in predicting ≥1 or ≥2 metabolic disorders were 2.88(2.15~3.86) and 6.83(4.47~10.44),respectively,which were similar with the corresponding values of WHtR[2.63(1.86~3.71) and 5.77(3.65~9.13)],as well as BMI[3.03(2.17~4.23) and 6.35(4.03~10.00)]. Conclusions WC,WHtR and BMI are all important predictors for metabolic disorders in children and adolescents.Considering the similar performance of WC,WHtR and BMI,WHtR may be suitable to replace WC and BMI as an early warning predictor of metabolic disorders in children and adolescents.

Key words: waist circumference, waist-height ratio, body mass index, adolescent, metabolic disorders, abdominal obesity