关键词: 产前焦虑, 出生体重, 前瞻性研究, 新生儿

Abstract: Objective To explore the adverse effect of prenatal anxiety on neonatal birth weight (NBW). Methods A perspective study was conducted with 220 prenatal anxiety and 220 non-prenatal anxiety pregnant women selected from Xinhua hospital of Hubei province during Jun 2009 to Dec 2010.Those 220 prenatal anxiety pregnant women were further randomly divided into non-intervention group (n=110) and intervention group (n=110) who accepted the psychological intervention.The Self-Rating Anxiety Scale (SAS) was used to evaluate the participants' prenatal anxiety extension.Information of NBWs and LBW were extracted from hospital recorded. Results The average SAS score of intervention group significantly decreased after psychological intervention (P<0.001);the NBW of intervention group[(3 390±510) g] and blank group[(3 480±480) g] were significantly heavier than non-intervention group[(3 070±610) g](F=23.40,P<0.001).The gap between intervention group[(3 390±510) g] and blank group[(3 480±480) g] was tested non-significant.The incidences of LBW were significantly higher in non-intervention group than those of intervention group and blank group (P=0.031). Conclusion Prenatal anxiety may have adverse effect on NBW and psychological intervention may be helpful in relieving prenatal anxiety and further decreasing the adverse effect on NBW.

Key words: prenatal anxiety, birth weight, perspective study, neonatal