2023年美国儿科学会先天性甲状腺功能减低症筛查与管理指南解读

doi:10.11852/zgetbjzz2023-1186

摘要/Abstract

摘要： 先天性甲状腺功能减低症是儿童常见的甲状腺疾病,若未及时筛查、诊治可造成智力、体格发育不可逆的损伤。2023年1月美国儿科学会发布了关于先天性甲状腺功能减低症筛查与管理指南,对于先天性甲状腺功能减低症病理生理学、新生儿筛查方案与流程、影像学与基因学诊断、长期随访管理与评估等方面进行了详细阐述。本文参考国内外文献对指南重点内容进行解读,以便于我国儿科医生借鉴。

关键词: 先天性甲状腺功能减退症, 新生儿筛查, 诊断治疗, 管理, 指南解读

Abstract: Congenital hypothyroidism is a common thyroid disease in children. If it is not screened and treated in a timely manner, it can cause irreversible damage to intellectual and physical development. In January 2023, the American Academy of Pediatrics issued guideline on the screening and management of congenital hypothyroidism. The guideline provides detailed information on the pathophysiology of congenital hypothyroidism, neonatal screening programs and procedures, imaging and genetic diagnosis, long-term follow-up management, and evaluation. To make it more convenient for domestic pediatricians to use as a reference, this article provides an interpretation of some key contents by referring to domestic and foreign literature.

Key words: congenital hypothyroidism, newborn screening, diagnostic and treatment, management, guide interpretation

中图分类号:

R725.8

刘畅, 张立琴, 杜玮, 刘婷廷. 2023年美国儿科学会先天性甲状腺功能减低症筛查与管理指南解读[J]. 中国儿童保健杂志, 2024, 32(6): 637-642.

LIU Chang, ZHANG Liqin, DU Wei, LIU Tingting. Interpretation of guideline on the screening and management of congenital hypothyroidism issued by American Academy of Pediatrics in 2023[J]. Chinese Journal of Child Health Care, 2024, 32(6): 637-642.

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