人乳多不饱和脂肪酸含量与婴儿食物过敏关系的研究

黄于娟; 黎海芪

中国儿童保健杂志 ›› 2011, Vol. 19 ›› Issue (1) : 65-67.

临床研究与分析

人乳多不饱和脂肪酸含量与婴儿食物过敏关系的研究

黄于娟,黎海芪

作者信息 +

Correlation between contents of polyunsaturated fatty acid in human breast milk and food allergy in infants

HUANG Yu-juan, LI Hai-qi

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文章历史 +

摘要

【目的】研究人乳多不饱和脂肪酸(polyunsaturated fatty acid, PUFA)含量与婴儿发生食物过敏的关系。【方法】采集3~6月人乳喂养婴儿母亲的乳汁,高效液相色谱法法检测其中α-LNA、DHA(n-3组)和LA、AA含量(n-6组);按R.Sporik标准确立婴儿食物过敏,比较食物过敏与正常婴儿母亲乳汁中PUFA含量的差异性。【结果】 31例3~6月龄人乳喂养婴儿中10例发生食物过敏,过敏婴儿母亲乳汁中LA、AA及α-LNA含量增高(P<0.05)、DHA含量差异无统计学意义。【结论】食物过敏婴儿的母亲乳汁中α-LNA、LA、AA含量升高,提示人乳PUFA代谢异常可能与婴儿发生食物过敏有关。

Abstract

【Objective】 To explore the correlation between contents of α-LNA、DHA、AA and LA in human milk and the development of food allergy in infants. 【Methods】 Cross-sectional study was conducted; breastfed infants aged 3~6 months were enrolled as well as their mothers; human milk samples were collected in the out-patient clinic, contents of PUFAs in human milk were analysed with HPLC method. Infants were diagnosed as food allergy according to R.Sporik's method in our out-patient clinic. 【Results】 10 infants were diagnosed as food allergy, and 21 normal as control. Contents of α-LNA、AA and LA in human milk of food-allergy group were higher than those in control group(P<0.05), except the contents of DHA. 【Conclusions】 The results suggest that human milk rich in n-6 PUFA such as LA and AA may be a risk factor to the development of food allergy in infants.

导出引用

黄于娟,黎海芪. 人乳多不饱和脂肪酸含量与婴儿食物过敏关系的研究[J]. 中国儿童保健杂志. 2011, 19(1): 65-67

HUANG Yu-juan, LI Hai-qi. Correlation between contents of polyunsaturated fatty acid in human breast milk and food allergy in infants[J]. Chinese Journal of Child Health Care. 2011, 19(1): 65-67

中图分类号： R174

参考文献

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