关键词: 白细胞形态参数, 儿童外周血, 淋巴细胞颗粒度, 大颗粒淋巴细胞

Abstract: Objective To analyze the morphological parameters of peripheral blood leucocytes in children,and to find the clinical significance.Methods A total of 180 healthy children (under 15 years old) were enrolled in this study,and parameters of white blood cells were analyzed by Sysmex XE-2100 automatic blood analyzer.The parameter data and changes of white blood cells were analyzed by age 0～,1～,2～,6～,12～15 years old.Results The fluorescence of neutrophilic granulocytes (NEUT-X) of all age groups were 1 355.0±41.5,1 348.3±22.5,1 348.4±51.3,1 339.3±51.6,1 335.8±46.2 respectively,and there were no statistical difference among groups (P=0.292).The fluorescence intensity of neutrophilic nucleic acid (NEUT-Y) were 495.6±28.2,477.6±38.6,486.5±40.2,481.3±32.2,479.9±39.6 respectively,and there were no statistical differences (P=0.412).The fluorescence intensity of lymphocyte nucleic acid (LYMPH-Y) were 713.6±46.3,708.3±60.3,711.0±61.2,712.8±72.3,711.6±75.3,and there were no significiant differences among groups (P=0.115).The fluorescence intensity of lymphocyte(LYMPH-X) were 896.3±36.2,854.6±19.3,858.4±17.6,860.1±15.7,851.3±18.2,and there were statistical differences among groups (P=0.008).Conclusion The granularity of peripheral blood lymphocyte in healthy children under 1 year old is higher than that of other ages,which indicated 0~1 years old children have better immunity.

Key words: leukocyte morphological parameters, peripheral blood of children, lymphocyte granularity, macrogranular lymphocytes