Abstract: 【Objective】 To identify the trend of mortality from congenital malformation in children under 5 years old in Beijing from 2001 to 2010. 【Methods】 Data were obtained from the Beijing children mortality surveillance network. A descriptive analysis was performed on birth defect-specific mortality in children under 5 years old(U5MR). 【Results】 1)The birth defect-specific U5MR decrease from 227.1/10⁵ live births in 2001 to 97.1/10⁵ live births in 2010; 2)Congenital heart disease, neural tube defects, Down's syndrome were significantly decreased in urban and neural tube defects, Down's syndrome was not significant decrease in rural; 3)The Proportion of mortality due to major congenital malformation decrease from 29.2% in 2001 to 23.1% in 2010; 4)Mortality from congenital malformation in children under 5 years old mainly in infant, especially in neonate. 【Conclusions】 Congenital malformation has been the leading causes of death in children under 5 years old. Strengthen prevention and reduce congenital malformation of death in rural have been the important work for us.

Key words: death rate, congenital malformation, epidemiology, child

摘要： 【目的】 了解2001-2010年北京市5岁以下儿童先天异常死亡的变化趋势。 【方法】 采用北京市儿童生命监测网收集的数据,计算出5岁以下儿童先天异常死亡专率、构成比和年龄分布情况。 【结果】 1)北京市5岁以下儿童先天异常死亡专率由2001年的227.1/10⁵下降至2010年的97.1/10⁵;2)北京市城市先天心脏病、神经管畸形、先天愚型均显著下降;农村神经管畸形、先天愚型下降不显著;3)先天异常死亡占5岁以下儿童死亡的比例由2001年的29.2%下降至2010年的23.1%;4)5岁以下儿童先天异常死亡主要发生在婴儿期,尤其是新生儿期。 【结论】 北京市先天发育异常儿童死亡已经成为5岁以下儿童主要死因,需进一步加强农村地区相关疾病的预防水平。

关键词: 死亡率, 先天发育异常, 流行病学, 儿童