Objective To describe the relationship between physical growth and sex characteristics for males at puberty in order to add to the mounting evidence for the development of growth charts based on puberty phases. Methods Data about physical growth and sexual development of 9 767 school-aged males at age 6~19 years were obtained from part of the Beijing Child and Adolescent Metabolic Syndrome Study conducted in 2004.General characteristics of height and weight gains were compared and analyze based on the different Tanner stages of pubic hair and testicular volume and the different phases of puberty,respectively. Results 1) Height is taller and weight heavier in spermatorrhea adolescents than no-spermatorrhea,showing a narrowing trend in difference of the two groups from the age of 11 to 16 years.2)Comparing with the growth pattern without developmental stages,both height and weight are significantly lower at age 11~13 years in stage of PH1 or TV<4 mL,following a cross with higher then lower in stages of PH2,PH3 or 4 mL≤TV<20 mL,and slightly higher in stages of PH4,PH5 or TV≥20 mL.3) The growth patterns of height and weight at different puberty phases are different from those of ignoring puberty phases.Height is shorter and weight lighter for some of normal population at pre-puberty,and taller and heavier trends are observed among another of normal population at in-puberty and completing puberty.4) P3 and P97 percentiles of height and weight based on different puberty phases do not shift cross corresponding P1 and P99 percentiles based on ignoring puberty phase,respectively. Conclusions The classification method of pre-puberty,in puberty and completing puberty based on pubic hair and testicular volume is useful to construct the growth references of puberty phases.Shifting up or down a major empirical percentile may be helpful to adjust the effect of sex development on height and weight when using conventional growth chart for age to assess growth level of adolescents.
Key words
puberty /
sex characteristics /
height /
weight
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
References
[1] RCPCH launches new growth charts for school age children.Retrieved from http://www.rcpch.ac.uk/news/rcpch-launches-new-growth-charts-school-age-children.(2014-03-10)
[2] Wright CM,Williams AF,Elliman D,et al.Using the new UK-WHO growth charts[J].BMJ,2010,340:1140.
[3] Mumm R,Scheffler C,Hermanussen M.Developing differential height,weight and body mass index references for girls that reflect the impact of the menarche[J].Acta Paediatr,2014 Mar 9.doi:10.1111/apa.12625.[Epub ahead of print]
[4] Ma HM,Chen SK,Chen RM,et al.Pubertal Study Group of the Society of Pediatric Endocrinology and Genetic Disease,Chinese Medical Association.Pubertal development timing in urban Chinese boys[J].Int J Androl,2011,34(5 Pt 2):e435-445.
[5] Sun Y,Tao F,Su PY,et al.National estimates of pubertal milestones among urban and rural Chinese boys[J].Ann Hum Biol,2012,39(6):461-467.
[6] 孟祥睿,王海俊,付连国,等.中国11~15岁青春期男生遗精发生与身体形态发育的关系[J].中华预防医学杂志,2013,47(8):695-699.
[7] 阳益德,马军,付连国,等.中国11~15岁青春期女生月经初潮较早与形态发育的关系[J].中华预防医学杂志,2013,47(8):712-717.
[8] 侯冬青,李辉,孙淑英,等.北京市儿童青少年女性青春期性征发育流行病学研究[J].中国循证儿科杂志,2006,1(4):264-268.
[9] 张金山,侯冬青,李辉,等.北京市儿童青少年男性青春期性征发育流行病学研究[J].中国循证儿科杂志,2006,1(4):269-272.
[10] Marshall WA,Tanner JM.Variations in the Pattern of Pubertal Changes in Boys[J].Arch Dis Child,1970,45(239):13-23.
[11] Wright CM,Ahmed L,Dunger DB,et al.Can we characterise growth in puberty more accurately?Validation of a new Puberty Phase Specific (PPS) growth chart[J].Arch Dis Child,2012,97(S1):A100.
[12] Chipkevitch E.Clinical assessment of sexual maturation in adolescents[J].J Pediatr(Rio J),2001,77(S2):135-142.
[13] Cole TJ.The development of growth references and growth charts[J].Ann Hum Biol,2012,39(5):382-394.
[14] 李辉,季成叶,宗心南,等.中国0~18岁儿童青少年身高、体重的标准化生长曲线[J].中华儿科杂志,2009,47(7):487-492.