血清脑钠肽检测在新生儿疾病中的应用

中国儿童保健杂志 ›› 2012, Vol. 20 ›› Issue (3): 238-240.

血清脑钠肽检测在新生儿疾病中的应用

李晓莺,刘建红,潘艳艳

山东大学齐鲁儿童医院新生儿科,山东青岛 250022

收稿日期:2011-12-29 发布日期:2012-03-06 出版日期:2012-03-06
作者简介:李晓莺(1972-),女,山东人,主治医师,硕士学位,主要研究方向为新生儿疾病
基金资助:
山东省科技发展计划项目(2008GG30002016)

Received:2011-12-29 Online:2012-03-06 Published:2012-03-06

摘要/Abstract

摘要： 脑钠肽(brain natriuretic peptide,BNP) 主要由心室肌细胞合成和分泌,心室负荷和室壁张力的改变是刺激BNP分泌的主要条件,BNP水平在生后前几天明显增高,3~4 d时达到高峰,一周后水平开始下降,生后3月时接近成人水平。患有先天性心脏病的新生儿中,BNP水平明显增高。有明显症状的动脉导管未闭早产儿中,BNP明显增高;PPHN的患儿中,BNP水平显著增高;脑钠肽在严重败血症和败血症休克的患儿中,BNP水平明显增高。需要更多的临床的随机的大样本研究来证实BNP在新生儿疾病的作用。

中图分类号:

R722.1

李晓莺,刘建红,潘艳艳. 血清脑钠肽检测在新生儿疾病中的应用[J]. 中国儿童保健杂志, 2012, 20(3): 238-240.

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