肠道微生物与儿童呼吸道病毒感染的研究进展

doi:10.11852/zgetbjzz2022-0424

中国儿童保健杂志 ›› 2023, Vol. 31 ›› Issue (7): 766-769.DOI: 10.11852/zgetbjzz2022-0424

肠道微生物与儿童呼吸道病毒感染的研究进展

叶芝旭, 余福勋

贵州省人民医院儿科,中国卫生健康委员会肺脏免疫性疾病重点实验室,贵州省人民医院中心实验室,贵州贵阳 550002

收稿日期:2022-06-09 修回日期:2022-11-23 发布日期:2023-07-12 出版日期:2023-07-10
通讯作者: 余福勋, E-mail: yufuxun@126.com
作者简介:叶芝旭 (1987-),女, 贵州人,副主任医师,博士研究生,主要从事儿童呼吸道病毒感染及免疫学研究。
基金资助:
国家自然科学基金地区基金(81860003、81960001);贵州省科技厅支撑计划([2018]2785);贵州省卫生计生委科学技术基金项目(gzwjw2018-1-049);贵州省(第六批)高层次创新型人才(千层次)(GZSYQCC[2023]011)

Research progress of gut microbiota and respiratory virus infection in children

YE Zhixu, YU Fuxun

Department of Pediatrics, Guizhou Provincial People′s Hospital, Key Laboratory of Pulmonary Immune Diseases, Chinese Health Commission, Central Laboratory, Guizhou Provincial People′s Hospital, Guiyang, Guizhou 550002, China

Received:2022-06-09 Revised:2022-11-23 Online:2023-07-10 Published:2023-07-12
Contact: YU Fuxun, E-mail: yufuxun@126.com

摘要/Abstract

摘要： 肠道微生物在维持人体健康方面发挥着重要作用。病毒是儿童急性呼吸道感染最常见的病原。探讨肠道微生物与疾病之间的关系已成为当前的研究热点之一。越来越多的证据表明,肠道微生物可远程影响宿主的免疫反应,这对宿主的抗感染和防御至关重要。本文综述了肠道微生物对儿童呼吸道病毒感染的免疫调控作用,重点关注儿童常见的呼吸道合胞病毒及流感病毒感染,以期为儿童呼吸道病毒感染性疾病的防治提供新思路。

关键词: 肠道微生物, 呼吸道病毒, 感染, 儿童

Abstract: Gut microbiota plays an important role in maintaining human health.Viruses are the most common cause of acute respiratory tract infection in children.The relationship between gut microbiota and disease has become a hot topic of current research.There is increasing evidence that gut microbiota can remotely influence the host immune response, which is crucial to host defense against infection.This paper summarizes the research progress in the effect of gut microbiota on children′s respiratory tract immunity, focusing on the relationship between gut microbiota and defense against respiratory tract virus infection in children, so as to provide a new idea for the prevention and treatment of respiratory viral diseases in children.

Key words: gut microbiota, respiratory virus, infection, children

中图分类号:

R725.6

叶芝旭, 余福勋. 肠道微生物与儿童呼吸道病毒感染的研究进展[J]. 中国儿童保健杂志, 2023, 31(7): 766-769.

YE Zhixu, YU Fuxun. Research progress of gut microbiota and respiratory virus infection in children[J]. Chinese Journal of Child Health Care, 2023, 31(7): 766-769.

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肠道微生物与儿童呼吸道病毒感染的研究进展

Research progress of gut microbiota and respiratory virus infection in children

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