Abstract: Objective To detect and analyse mumps virus antibody levels of 3 to 15 years old children and adolescents in High-tech Industrial Development Zone,Urumqi,and provide the basis for the formulation and adjustment mumps prevention and control strategies. Method By adopting the cluster sampling method,560 students aged 3 to 15 were select from six schools in High-tech Industrial Development Zone,Urumqi.The antibody of serum was detected by ELISA. Results The mumps virus antibody positive average rate was 78.92% in different age groups,the highest positive rate was found in the age group of 7~ and 14~15 up to 90%,the positive rate was decreased with the growth of age in the other groups,and was at its lowest in 5 to 12 years old; There was no significantly difference of mumps virus antibody positive rate in different gender and nation; Students of residence antibody positive rate was higher than shack students,and antibody positive rate was in proportion to the doses of vaccination. Conclusion Mumps virus antibody-positive rate in 3 to 15 years old students is lower in high-tech industrial development zone,Urumqi.The inoculating units should strengthen the management of floating children,improve the mumps vaccination rates in school-age children and succeed in doing preschool check verification and second dose of strengthening to prevent the disease outbreaks in our region.

Key words: mumps, antibody level, immune

摘要： 目的 检测并分析乌鲁木齐市高新区3~15岁在校生腮腺炎病毒抗体水平,为腮腺炎预防控制工作提供科学依据。方法 采用整群抽样法抽取高新区六所学校3~15岁在校生共560人,采用酶联免疫法定性测定血清腮腺炎病毒抗体。结果 各年龄组腮腺炎病毒抗体总体阳性率为78.92%,7岁~和14~15岁年龄组阳性率最高均为90%,其余各组阳性率随年龄增加而降低,5岁~与12岁~达最低值;不同性别、民族腮腺炎病毒抗体阳性率无差异;常住户籍儿童抗体阳性率高于流动儿童,且抗体阳性率与接种剂次成正比。结论 高新区3~15岁在校生腮腺炎病毒抗体阳性率较低,为预防该疾病在本区爆发,各接种点应加强对流动儿童接种管理,提高适龄儿童含腮腺炎成分疫苗接种率,做好学前查验证及第二剂次加强工作。

关键词: 流行性腮腺炎, 抗体水平, 免疫效果