Abstract: Objective To understand epidemiologic features of Nanning city from 2008 to 2011 and provide reference for the prevention and control of hand foot mouth disease. Method Using descriptive epidemiological method,the data of hospital outpatient and inpatient children with hand foot and mouth disease were analyzed. Results A total of 9 280 cases were reported under the jurisdiction of the municipality of Nanning six urban areas from 2008 to 2011.Xingning and Xixiangtang district had more incidence,accounted for 77.84%,the peak incidence was obseved from March to July,,sex ratio was 1.65∶1,major violations from scattered children and preschool children,was 97.37%,pathogen detection showed EV71,CoxA16 incidence,age was ranged from 6 months to 3 years,accounted for 84.67%,the incidence rate was quite low under 6 months,accounting for only 2.22%;treatment rate within 3 days after onset was high (95.13%),mild patient with outpatient treatment accounted for 84.94%,accounting for 15.06% of inpatient treatment. Conclusions Hand-foot-mouth' disease is mainly composed of EV71 or CoxA16 in Nanning city of 2008-2011.Summer peak,scattered children and kindergarten children,male were more incidence of primary group,infant under 6 months may have protective antibodies,most mild cases of outpatient service cures.

Key words: hand-foot-mouth disease, epidemiology, children

摘要： 目的 了解南宁市城区2008-2011年手足口病的流行病学特征,为防控手足口病提供参考。 方法 运用描述性流行病学方法,对本院门诊和住院手足口病患儿资料进行分析。 结果 2008-2011年南宁市所辖六城区均有病例报告,共9 280例,兴宁和西乡塘两区发病较多,占77.84%,呈全年散发,发病高峰期为3~7月,男女性别比为1.65∶1,主要侵犯散居儿童和托幼儿童,两者占97.37%,病原体检测显示以EV71、CoxA16为主,高发年龄6个月~3岁,占84.67%,6月以下发病率相当低,仅占2.22%;发病后3 d内就诊率高达95.13%,轻症病人门诊治疗占84.94%,住院治疗占15.06%。 结论 2008-2011年南宁市城区手足口病主要由EV71或CoXA16引起,六城区均有发病,夏季高发,散居儿童和托幼儿童是发病主要人群,男性高于女性,6月以下婴儿可能存在保护性抗体,绝大部分轻症患儿门诊治愈。

关键词: 手足口病, 流行病学, 儿童