doi:10.11852/zgetbjzz2014-22-12-15

Abstract

摘要： 神经发育性疾病病因复杂,由遗传和环境因素共同决定,其中遗传因素起重要作用。基于致病基因的研究是认识疾病的生物学基础的重要方法。锌指蛋白804A(zinc finger protein 804A,ZNF804A)是基于“常见疾病,常见变异”假说而开展的全基因组关联研究发现的与精神疾病相关性最强的易感基因之一,受到了研究者的极大关注。本文将对ZNF804A在精神分裂症和孤独谱系障碍等神经发育性疾病中的研究进展做一综述。

关键词: ZNF804A基因, 精神分裂症, 孤独谱系障碍, 全基因组关联研究

CLC Number:

R749.94

张林娜,公晓红,王楚,杜亚松. ZNF804A基因在神经发育性疾病中的研究进展[J]. 中国儿童保健杂志, 2014, 22(12): 1280-1282.

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ZNF804A基因在神经发育性疾病中的研究进展

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