Abstract: Objective To investigate the reliability and validity of Childhood Autism Spectrum Test(CAST)as a screening tool in China. Methods CAST Chinese version was developed by translating,back translating,and comparing repeatedly.A sample of 38 autistic children were recruited as patient group,twelve mental retarded children and fifty-nine typical developing children were recruited as control group in Hangzhou.Their parents completed CAST Chinese version. Results Internal consistency reliability and criterion-related validity of CAST Chinese version were good.Twenty-five of thirty-one scoring items had good discrimination index.At a designated cut-point of 16,the sensitivity of CAST Chinese version was 0.974,the specificity was 0.983 and positive predictive value (PPV) was 0.974.There was no significant difference between children younger and older than 4 years old. Conclusions Chinese version of Childhood Autism Spectrum Test(CAST)has good reliability and validity.It can be used to screen autistic children older than 2.5 years old.However,several items need to be improved in further study.

Key words: autism, screen, Childhood Autism Spectrum Test, children

摘要： 目的 研究儿童孤独症测验(Childhood Autism Spectrum Test,CAST)作为孤独症筛查量表在我国应用的可靠性及有效性。方法 对CAST进行多轮翻译、回译和校对形成中文版,以杭州市38名孤独症儿童为病例组,12名精神发育迟滞儿童和59名正常儿童为对照组,对儿童家长进行问卷调查。结果 CAST中文版具有良好的内部一致性信度和效标关联效度。31个计分题目中有25个具有良好的区分度,当临界分为16分时,量表具有最佳敏感度、特异性和阳性预测值。不同年龄组儿童的CAST总分无差异。结论 儿童孤独症测验(CAST)中文版有良好的信效度,适用于2.5岁以上儿童孤独症的筛查,但个别题目仍待完善。

关键词: 孤独症, 筛查, CAST, 儿童