脑性瘫痪共病癫痫的遗传因素、危险因素及发病机制

公超; 连贝贝; 李雪梅; 张朋; 宋凡旭; 郭津

doi:10.11852/zgetbjzz2023-0344

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中国儿童保健杂志 ›› 2024, Vol. 32 ›› Issue (2) : 174-180. DOI: 10.11852/zgetbjzz2023-0344

综述

脑性瘫痪共病癫痫的遗传因素、危险因素及发病机制

公超¹, 连贝贝¹, 李雪梅^1,2, 张朋^1,3, 宋凡旭^1,2, 郭津^1,3

作者信息 +

Genetic factors, risk factors and pathogenesis of cerebral palsy comorbid epilepsy

GONG Chao¹, LIAN Beibei¹, LI Xuemei^1,2, ZHANG Peng^1,3, SONG Fanxu^1,2, GUO Jin^1,3

Author information +

文章历史 +

摘要

相较于一般人群,癫痫在脑性瘫痪(CP)人群中患病率很高,是CP严重程度的标志,也是影响CP儿童早期生存率和未来生活质量的重要因素,因此对于CP和癫痫的病因研究尤为重要。本研究将从遗传因素、危险因素以及病理生理机制方面总结CP和癫痫的共患病因,以期为今后研究提供参考。

Abstract

Compared to the general population, there is a higher prevalence of epilepsy in individuals with cerebral palsy (CP). Epilepsy serves as an indicator of CP severity and has a significant impact on the early survival and future quality of life of children with CP. Therefore, it is crucial to investigate the shared mechanisms underlying CP and epilepsy. This study aims to summarize the comorbidity of CP and epilepsy from genetic factors, risk factors, and pathophysiological mechanisms, in order to provide a reference for further research.

导出引用

公超, 连贝贝, 李雪梅, 张朋, 宋凡旭, 郭津. 脑性瘫痪共病癫痫的遗传因素、危险因素及发病机制[J]. 中国儿童保健杂志. 2024, 32(2): 174-180 https://doi.org/10.11852/zgetbjzz2023-0344

GONG Chao, LIAN Beibei, LI Xuemei, ZHANG Peng, SONG Fanxu, GUO Jin. Genetic factors, risk factors and pathogenesis of cerebral palsy comorbid epilepsy[J]. Chinese Journal of Child Health Care. 2024, 32(2): 174-180 https://doi.org/10.11852/zgetbjzz2023-0344

中图分类号： R742.1 R742.3

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