【Objective】 To study the behavioral problems and related factors in school-age children with asthma. 【Methods】 Followed up 92 cases of school-age children with asthma, they were investigated with self edited general questionnaire and parents' chart of Rutter children's behavior questionnaire. 92 cases of healthy children were sampled as control group matched by age, sex etc, they also were investigated with parents' chart of Rutter children's behavior questionnaire. 【Results】 Among 50 cases of boys with asthma, 22 cases (44.00%) had behavioral problems, of which 19 cases (38.00%) had violation discipline and 15 cases (30.00%) had neurotic behavior. The rates were significantly higher those of control group(all P＜0.05). Among 42 cases of girls with asthma, 17 cases (40.48%) had behavioral problems, of which 15 cases (35.71%) had neurotic behavior. Significantly differences were found between two female groups(P＜0.05),but no significantly difference was found in two groups with violation discipline(χ²=0.454,P＞0.500). Multiple step-wise regression analysis suggested that the factors increasing behavioral problems of school-age children with asthma included the patient's age, onset duration, the annual average onset frequency and days, the recurrent numbers, weight-for-age and the days and the amount of intravenous steroid.The factors reducing behavioral problems of school-age children with asthma involved the first onset age, the actual proportion of learning time and the daily mean duration of outdoors activity. 【Conclusions】 Behavioral problems are significantly prevalent in asthma and much attention should be paid to them.