Objective To investigate psychological and behavioral problems in children and adolescents with severe beta-thalassemia major (β-TM), and to analyze their influencing factors, so as to provide basis for targeted interventions to promote the psychological and behavioral health of β-TM patients. Methods A convenience sampling method was used to select 146 pediatric and adolescent patients with β-TM from the pediatrics department a tertiary general hospital in the border region of Guangxi, Yunnan, and Guizhou provinces between August 2022 and February 2023. Data were collected using a demographic questionnaire, the Conners′ Parent Symptom Questionnaire, the Simplified Coping Style Questionnaire, and the Parental Feeding Style Scale. Multivariate Logistic regression analysis was used to identify factors influencing the psychological and behavioral problems of these patients. Results Among the 146 β-TM patients, the total score of psychological and behavioral problems was 17.08 ± 13.62, with a detection rate of 39.0%. Multivariate Logistic regression analysis showed that protective factors of psychological and behavioral problems in β-TM children included age (13 -18 years old), parental education level of high school or above(senior high school/vocational school,college andabove), and emotionally warm parenting style(OR=0.778,0.730,0.802,0.703), while the risk factors included heavy economic burden due to the disease, migrant family status, negative coping styles of parents, and overprotective parenting style (P＜0.05). Gender, being an only child, and regular iron chelation therapy were not significantly associated with the occurrence of psychological and behavioral problems (P>0.05). Conclusion Psychological and behavioral problems are prominent among β-TM patients and are closely related to patient age, family structure, and parental education levels. Targeted interventions should be implemented to improve the psychological and behavioral health of these patients.
Key words
β-thalassemia major /
children and adolescents /
psychological and behavioral problems
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