Abstract: 【Objective】 To investigate the main effect factors associated with neonatal respiratory failure(NRF). 【Methods】 Total of 188 neonatals with NRF and 190 neonatals with non-NRF of NICU were selected in the same period. The data of NRF were analyzed with case-control study. 【Results】 Tweleve factors were proved to be statistically significant difference. including residence, mode of delivery, multiple pregnancy, premature birth, pregnancy disease, fetal distress, amniotic fluid aspiration, hypoxic-ischemic encephalopathy, birth asphyxia,respiratory distress syndrome, congenital heart disease, meconium aspiration syndrome. 【Conclusions】 Controlling these risk factors of NRF is of great practical significance to reducing the incidence and mortality of NRF.

Key words: respiratory failure, case-control study, neonatal

摘要： 【目的】 探讨分析新生儿呼吸衰竭相关影响因素,为治疗提供科学依据。 【方法】 对新生儿重症监护病房收治的188例呼吸衰竭患儿和190例非呼吸衰竭患儿资料进行病例对照回顾性研究,分析其影响因素。 【结果】 与同期重症监护病房住院非NRF患儿对照比较,居住地、分娩方式、多胎妊娠、早产、母亲疾病、宫内窘迫、羊水吸入、缺氧缺血性脑病、出生窒息、呼吸窘迫综合征、先天性心脏病、胎粪吸入综合征共12项因素差异有统计学意义。 【结论】 控制和干预新生儿呼吸衰竭影响因素对降低新生儿呼吸衰竭的发病率、病死率有着较大实际意义。

关键词: 呼吸衰竭, 病例对照, 新生儿