Objective To analyze the pregnancy outcome of the fetus with omphalocele, so as to provide reference for clinical diagnosis, treatment and prognosis of the disease. Methods The data of 44 cases of fetal omphalocele diagnosed prenatal in two large Grade A hospitals in Xi′an were retrospectively analyzed. According to the size of the fetal omphalocele at birth, children were divided into two groups: omphalocele ≤5cm group (n=21) and omphalocele >5cm group(n=23) (50% - 75% of the liver was in the capsule). Data on pregnant women′s age, time of delivery, mode of delivery, whether there were other malformations, gestational weeks at delivery, birth weight of newborns, adverse neonatal outcomes, neonatal sex, neonatal hospitalization time, neonatal fasting time, whether there were pregnancy complications during pregnancy, and long-term follow-up of neonatal development were collected and analyzed. Results There was no significant difference between the two groups in age, gestational age, time of delivery, mode of delivery, complications during pregnancy, birth weight and newborn sex (P>0.05). Compared with the omphalocele ≤5cm group, the hospital stay and fasting time of neonates in the omphalocele >5cm group were longer, and the incidence of adverse outcomes was higher, with statistical significance (t=3.054,0.918,χ2=5.750,P<0.05). In the long-term follow-up, there were no significant differences in postoperative feeding difficulties, motor function, cognition, weight development, height development, behavior and the rate of second operation between the two groups (P>0.05). Conclusions Most newborns with omphalocele ≤5cm have a good prognosis. Attention should be paid to fetal health examination, and regular ultrasound should be performed during pregnancy to observe the development of fetal umbilical cord, and effective prevention and control measures should be taken to diagnose the malformation of omphalocele.
Key words
fetal omphalocele /
pregnancy outcome /
length of hospital stay required for neonatal operation /
fasting time of newborn /
long-term development follow-up
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