Abstract: 【Objective】 To observe the bone age development in children with hypothyroidism and explore the potential applications in diagnosis and therapy of hypothyroidism. 【Method】 It was observed that 37 children's X-ray films of left hands and wrists and applied method for assessing bone age of Chinese children to score their bone age. 【Result】 The bone age of children with hypothyroidism were younger than their chronological age and the bone age caughted up the chronological age after treatment in the followed 2~3 years. 【Conclusion】 Bone age inspection has important instructional significance in diagnosis and treatment of hypothyroidism in children.

Key words: bone age, hypothyroidism, method for assessing bone age, thyroid hormone

摘要： 【目的】 观察甲状腺功能减低症患儿的骨龄发育情况,探讨骨龄测定在甲状腺功能减低症患儿诊断及治疗中的意义。 【方法】 对在本院内分泌门诊确诊为甲状腺功能减低症的37例患儿进行随访,于治疗前及治疗过程中拍摄左手及腕部正位X线片,应用《中国儿童骨龄评分法》进行骨龄评分,计算出骨龄。 【结果】 甲状腺功能减低症患儿的骨龄明显小于年龄,其差异有统计学意义(P<0.01);经替代治疗约2～3年后,骨龄与年龄相近。 【结论】 骨龄测定对甲状腺功能减低症患儿的诊断及疗效判断有重要的临床指导意义。

关键词: 骨龄, 甲状腺功能减低症, 骨龄评分法, 甲状腺激素