Regional homogeneity in the patients with conduct disorder: a resting-state functional magnetic resonance imaging study

WANG Peng-peng; ZHANG Jin-song; XIA Wei-ping; LIAO Xiang-peng

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Chinese Journal of Child Health Care ›› 2011, Vol. 19 ›› Issue (3) : 210-213.

Regional homogeneity in the patients with conduct disorder: a resting-state functional magnetic resonance imaging study

WANG Peng-peng¹, ZHANG Jin-song^1,2, XIA Wei-ping², LIAO Xiang-peng¹

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Abstract

【Objective】 To investigate the differences of brain spontaneous activity in resting state between adolescents with conduct disorder(CD) and matched controls using function magnetic imaging(fMRI). 【Method】 11 cases diagnosed with DSM-IV and 11 normal controls underwent resting-state fMRI, the data were analyzed using a newly reported method called Regional Homogeneity(ReHo) to analyze fMRI data between CD and normal controls. 【Result】 Compared with normal controls, CD showed decreased ReHo in bilateral frontal lobe and left inferior parietal and precuneus and increased in left temporal lobe and left fusiform gyrus and right anterior cingulated. 【Conclusion】 The results suggest that CD showed abnormal activity in resting state compared with the normal controls.

Key words

conduct disorder / magnetic resonance imaging / regional homogeneity

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WANG Peng-peng, ZHANG Jin-song, XIA Wei-ping, LIAO Xiang-peng. Regional homogeneity in the patients with conduct disorder: a resting-state functional magnetic resonance imaging study[J]. Chinese Journal of Child Health Care. 2011, 19(3): 210-213

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