Study on correlation between B/A Ratio and abnormal brain MRI in neonates with severe hyperbilirubinemia.

REN Chang-jun,HAO Ling,CHENG Si-si,DENG Yan-dong,QIU hai-nan.

Chinese Journal of Child Health Care ›› 2016, Vol. 24 ›› Issue (5) : 499-501.

PDF(450 KB)
PDF(450 KB)
Chinese Journal of Child Health Care ›› 2016, Vol. 24 ›› Issue (5) : 499-501. DOI: 10.11852/zgetbjzz2016-24-05-16

Study on correlation between B/A Ratio and abnormal brain MRI in neonates with severe hyperbilirubinemia.

  • REN Chang-jun1,HAO Ling1,CHENG Si-si1,DENG Yan-dong2,QIU hai-nan3.
Author information +
History +

Abstract

Objective To investigate the relationship with neonatal hyperbilirubinemia between total bilirubin / albumin ratio(B/A)with brain magnetic resonance imaging (MRI) abnormalities and its clinical significance. Methods A total of 162 neonates hyperbilirubinemia (total serum bilirubin ≥342.2 μmol / L) between January 2013 and January 2014 enrolled in the study.They were divided into two groups,according to the Results of brain MRI:normal MRI group (n=126)and abnormal MRI group (n=36).Retrospective analysis of the relationship between B/A ratio of brain magnetic resonance imaging. Result The Results showed that the abnormal MRI group had a higher B/A ratio compared with the normal MRI group.it reached statistical significance (P<0.05). Conclusions High B/A ratio is a risk factor for abnormal MRI neonates with severe hyperbilirubinemia,which is the reason that could cause neurobehavioral sequelae of neonates.Primary hospital through observe B/A,high B/A ratiowith severe hyperbilirubinemia shoud active cut down jaundice,reduce neurobehavioral sequelae of neonates,enhance follow-up of high rise children.

Key words

hyperbilirubinemia / magnetic resonance imaging / B/A ratio

Cite this article

Download Citations
REN Chang-jun,HAO Ling,CHENG Si-si,DENG Yan-dong,QIU hai-nan.. Study on correlation between B/A Ratio and abnormal brain MRI in neonates with severe hyperbilirubinemia.[J]. Chinese Journal of Child Health Care. 2016, 24(5): 499-501 https://doi.org/10.11852/zgetbjzz2016-24-05-16

References

[1] 邵肖梅,叶鸿瑁,丘小汕.实用新生儿学[M].4版.北京:人民卫生出版社,2011:222-227.
[2] Esfandiarpour B,Ebrahimi H,Karkan MF,et al.Neonatal exchange transfusion for hyperbilirubinemia in Guilan (the north province of Iran):a 3-year experience[J].Turk J Pediatr,2012,54(6):626-631.
[3] 庄严,李贵南,周勇,等.重度高胆红素血症新生儿总胆红素/白蛋白比值及酸中毒与脑干听觉诱发电位异常的关系[J].中国当代儿科杂志,2013,15(5):332-336.
[4] Campistol J,Galvez H,Cazorla AG,et al.Neurological dysfunction induced by bilirrubin [J].Neurología,2012,27(4):202-211.
[5] Coskun A,Yikilmaz A,Kumandas S,et al.Hyperintense globus palliduson T1-weighted MRI imaging in acute kernicterus:is it common or rare[J].Eur Radiol,2005,15(6):1263-1267.
[6] Govaert P,Lequin M,Swarte RY,et al.Changes in globus palli-dus with (pre)term kernicterus[J].Pediatrics,2003,112(6 Pt1):1256-1263.
[7] 刘辉,潘家华,闵红,等.新生儿高胆红素血症总胆红素/白蛋白比值 与脑干听觉诱发电位的关系[J].临床儿科杂志,2012,29(9):841-844.
[8] 翁淑萍,施跃全,方如旗,等.新生儿急性胆红素脑病的核磁成像表现极其诊断价值[J].福建医科大学学报,2012,46(1):64-67.
[9] 廖伟华,王小宜,吴武林,等.MRII 鉴别新生儿缺氧缺血性脑病与急性胆红素脑病的价值[J].中国当代儿科志,2009,11(1):181-184.
[10] 杜琨,张路,吴玉芹,等.新生儿重度胆红素血症176例病因分析[J].中国中西医结合儿科学,2009,1(6):555-556.
[11] 吕峻峰,杨冰岩,王维琼,等.严重高胆红素血症新生儿急性胆红素脑病危险因素分析[J].中国新生儿科杂志,2014,29(4):242-246.
PDF(450 KB)

Accesses

Citation

Detail

Sections
Recommended

/