Abstract: 【Objective】 To study the pattern of psychiatric comorbidity in school-age children with Asperger syndrome which may provide evidence for making a comprehensive intervention plans for them. 【Methods】 A follow-up study of a clinic sample of 117 school-age children with Asperger syndrome was conducted a retrospective review to examine the psychiatric disorders associated with them. 【Results】 More than half (59.8%)had at least one another psychiatric disorder diagnosis in which attention deficit hyperactivity disorder was the most common which accounted for 87.1%, and 22.9% of the comorbid psychiatric disorders were multiple. There were significant differences in VIQ,FIQ but not in PIQ between children with and without psychiatric comorbidity. No statistically significant difference was found with respect to gender whether the psychiatric comorbidity was diagnosed. 【Conclusion】 Psychiatric comorbidity in Asperger syndrome is very common, routine evaluation of psychiatric comorbidity in children with AS is necessary so that they can get appropriate treatments.

Key words: Asperger syndrome, comorbidity, attention deficit hyperactivity disorder

摘要： 【目的】 初步探讨学龄Asperger综合征(Asperger syndrome, AS)儿童共患精神疾病的模式,为系统评估及合适的干预计划提供依据。 【方法】 对117例门诊确诊为Asperger综合征(采用DSM-IV标准)的学龄儿童进行回顾性分析,调查他们共患其它精神障碍的模式及有关因素。 【结果】 发现超过一半以上患者(59.8%)共患至少一种精神疾病,其中以ADHD最常见,占87.1%,而且共患病往往是多重的,占22.9%。无精神共患病的AS儿童其平均VIQ、FIQ(分别106.1±18.2;99.3±18.6)显著高于有精神共患病的AS儿童平均VIQ、PIQ(分别96.6±19.7;89.5±19.6)(P＜0.05),两者的PIQ差异无统计学意义(P＞0.05)。 【结论】 AS患者共患其它精神疾病是一个普遍现象,临床中对AS儿童应常规进行精神共患病筛查以便得到及时有效的治疗。

关键词: Asperger综合征, 共患病, 注意缺陷多动障碍