Psychiatric comorbidity of school-age children with Asperger syndrome: a preliminary and clinic-based study
- CEN Chao-qun, TANG Chun, ZOU Xiao-bing, LI Jian-ying, DENG Hong-zhu
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Abstract
【Objective】 To study the pattern of psychiatric comorbidity in school-age children with Asperger syndrome which may provide evidence for making a comprehensive intervention plans for them. 【Methods】 A follow-up study of a clinic sample of 117 school-age children with Asperger syndrome was conducted a retrospective review to examine the psychiatric disorders associated with them. 【Results】 More than half (59.8%)had at least one another psychiatric disorder diagnosis in which attention deficit hyperactivity disorder was the most common which accounted for 87.1%, and 22.9% of the comorbid psychiatric disorders were multiple. There were significant differences in VIQ,FIQ but not in PIQ between children with and without psychiatric comorbidity. No statistically significant difference was found with respect to gender whether the psychiatric comorbidity was diagnosed. 【Conclusion】 Psychiatric comorbidity in Asperger syndrome is very common, routine evaluation of psychiatric comorbidity in children with AS is necessary so that they can get appropriate treatments.
Key words
Asperger syndrome / comorbidity / attention deficit hyperactivity disorder
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References
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[3] Howlin P. Outcome in Adult Life for more Able Individuals with Autism or Asperger[J]. Autism,2000,4:63-83.
[4] Ghaziuddin M, Weidmer-Mikhail E, Ghaziuddin N. Comorbidity of Asperger syndrome: a preliminary report[J]. Journal of Intellectual Disability Research,1998,42:279-283.
[5] Simonoff E, Pickles A, Charman T, et al. Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample[J]. Journal of the American Academy of Child & Adolescent Psychiatry,2008,47:921-929.
[6] Gillberg C, Billstedt E. Autism and Asperger syndrome: coexistence with other clinical disorders[J]. Acta Psychiatrica Scandinavica,2000,102:321-330.
[7] Mattila ML, Hurtig T, Haapsamo H, et al. Comorbid psychiatric disorders associated with asperger syndrome/high-functioning autism: a community- and clinic-based study[J]. Journal of Autism and Developmental Disorder,2010,Feb23. [Epub ahead of print].
[8] Martin A, Scahill L, Klin A, et al. Higher-functioning pervasive developmental disorders: rates and patterns of psychotropic drug use[J]. Journal of the American Academy of Child & Adolescent Psychiatry,1999,38:923-931.
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[10] Amy MS, Amy KW, Doris AT. Brief report: attention differences in asperger syndrome[J]. Journal of Autism and Developmental Disorders,2002,32:333-336.
[11] Howlin P. Outcome in Adult Life for more Able Individuals with Autism or Asperger Syndrome[J]. Autism,2000,4:63-83.
[12] Aron-Cohen S, Scahill VL, Izaguirre S. The prevalence of Gilles de la Tourette syndrome in children and adolescents with autism: A large scale study[J]. Psychological Medicine,1999,29:1151-1159.
[13] Ringman JM, Jankovic J. Occurrenceof tics in Asperger's syndrome and autistic disorder[J]. Journal of Child Neurology,2000,15:394-400.
[14] Kadesjo B, Gillberg C. Tourette's disorder: Epidemiology and comorbidity in primary school children[J]. Journal of the American Academy of Child & Adolescent Psychiatry,2000,39:548-555.
[15] Sverd J. Psychiatric disorders in individuals with pervasive developmental disorder[J]. Journal of Psychiatric Practice,2003,9:111-127.
[16] Volkmar FR, Cohen DJ. Comorbid Association of Autism and Schizophrenia[J]. America Journal of Psychiatry,1991,148:1705-1707.
[17] Hutton J. New-onset psychiatric disorders in individuals with autism[J]. Autism,2008,12:373-390.
[18] Clarke DJ, Baxter M, Perry D, et al. The diagnosis of affective and psychotic disorders in adults with autism: seven case reports[J]. Autism,1999,3:149-164.
