Neurodevelopment of preterm infants

doi:10.11852/zgetbjzz2020-1400

Abstract

Abstract: The survival rate of premature infants has been significantly improved with the progress of medicine.However, the incidence of neurodevelopmental disorders in survival preterm infants is significantly higher than that in normal full-term newborns.This paper briefly summarizes the related risk factors, possible neurodevelopmental disorders and comprehensive management of preterm infants, in order to remind parents and clinicians to pay more attention to the developmental disorders and intervention of preterm infants.

Key words: preterm infants, neurodevelopment, risk factors, intervention

摘要： 随着医学的进步, 早产儿的成活率显著提高。但早产儿的神经发育障碍性疾病的发生率明显高于正常足月新生儿。本文简单总结影响早产儿神经发育的相关危险因素、可能出现的神经发育障碍和综合管理, 旨在提醒家长和临床医生重视早产儿的神经发育和干预。

关键词: 早产儿, 神经发育, 危险因素, 干预

CLC Number:

:R174

HAN Ying. Neurodevelopment of preterm infants[J]. journal1, 2020, 28(8): 837-840.

韩颖. 早产儿的神经发育[J]. 中国儿童保健杂志, 2020, 28(8): 837-840.

References

[1] Martin J, Hamilton B, Osterman MJK, et al.Births in the United States[J].NCHS Data Brief, 2016, 287.
[2] Flood K, Malone FD.Prevention of preterm birth[J].Semin Fetal Neonatal Med, 2012, 17(1):58-63.
[3] Rogers CE, Lean RE, Wheelock MD, et al.Aberrant structural and functional connectivity and neurodevelopmental impairment in preterm children[J].J Neurodev Disord, 2018, 10(1):38.
[4] van Vliet EO, de Kieviet JF, van der Voorn JP, et al.Placental pathology and long-term neurodevelopment of very preterm infants[J].Am J Obstet Gynecol, 2012, 206(6):489.e1-7.
[5] Leppnen M, Ekholm E, Palo P, et al.Abnormal antenatal Doppler velocimetry and cognitive outcome in very-low-birth-weight infants at 2 years of age[J].Ultrasound Obstet Gynecol, 2010, 36(2):178-185.
[6] Ekblad M, Lehtonen L, Korkeila J, et al.Maternal smoking during pregnancy and the risk of psychiatric morbidity in singleton sibling pairs[J].Nicotine Tob Res, 2017, 19(5):597-604.
[7] Heinonen K, Rikknen K, Pesonen AK, et al.Longitudinal study of smoking cessation before pregnancy and children's cognitive abilities at 56 months of age[J].Early Hum, 2011, 87(5):353-359.
[8] Milla KY, Eeva E, Mikael E, et al.Prenatal risk factors for adverse developmental outcome in preterm infants-systematic review[J].Front Psychol, 2019, 10(595):1-12.
[9] Tian Y, Zhang C, Yu G, et al.Influencing factors of the neurodevelopment of high-risk infants[J].Gen Psychiatr, 2018, 31(3):e100034.
[10] Rogers EE, Hintz SR.Early neurodevelopmental outcomes of extremely preterm infants[J].Semin Perinatol, 2016, 40(8):497-509.
[11] Bhutta AT, Cleves MA, Casey PH, et al.Cognitive and behavioraloutcomes of school-aged children who were born preterm:a meta-analysis[J].JAMA, 2002, 288(6):728-737.
[12] Aarnoudse-Moens CS, Weisglas-Kuperus N, van Goudoever JB, et al.Meta-analysis of neurobehavioral outcomes in very preterm and/or very low birth weightchildren[J].Pediatrics, 2009, 124(2):717-728.
[13] Gathercole SE.The development ofmemory[J].J Child Psychol Psych, 1998, 39:3-27.
[14] van Houdt CA, Oosterlaan J, van Wassenaer-Leemhuis AG, et al.Executive function deficits in children born preterm or at low birth weight:a meta-analysis[J].Dev Med Child Neurol, 2019, 61(9):1015-1024.
[15] Albaugh M, Ducharme S, Karama S, et al.Anxious/depressed symptoms are related to microstructural maturation of white matter in typically developing youths[J].Dev Psychopathol, 2017, 29(3):751-758.
[16] Billeci L, Calderoni S, Tosetti M, et al.White matter connectivity in children with autism spectrum disorders:a tract-based spatial statistics study[J].BMC Neurol, 2012, 12:148.
[17] Solso S, Xu R, Proudfoot J, et al.Diffusion tensor imaging provides evidence of possible axonal over connectivity in frontal lobes in autism spectrum disorder toddlers[J].Biol Psychiatry, 2016, 79:676-684.
[18] Johnson S, Marlow N.Preterm birth and childhood psychiatricdisorders[J].Pediatr Res, 2011, 69:11R-18R.
[19] Campbell-Yeo ML, Disher TC, Benoit BL, et al.Understanding kangaroo care and its benefits to preterm infants[J].Pediatr Health Med Ther, 2015, 6:15-32.
[20] Schneider N, Garcia-Rodenas CL.Early nutritional interventions for brain and cognitive development in preterm infants:a review of the literature[J].Nutrients, 2017, 9(3):187.
[21] 中华人民共和国国家卫生健康委员会.早产儿保健工作规范[EB/OL].(2017-03-03).http://www.nhc.gov.cn/zwgk/jdjd/201703/0816ecd330c04c338c3fd468f1baf29f.shtml
[22] Weuve J, Sanchez BN, Calafat AM, et al.Exposure to phthalates in neonatal intensive care unit infants:Urinary concentrations of monoesters and oxidativemetabolites[J].Environ Health Persp, 2006, 114(9):1424-1431.
[23] Brown G.NICU noise and the preterminfant[J].Neonatal Network, 2009, 28(3):165-173.
[24] Picciolini O, Porro M, Meazza A, et al.Early exposure to maternal voice:Effects on preterm infantsdevelopment[J].Early Hum Dev, 2014, 90(6):287-292.
[25] Miller CL, White R, Whitman TL, et al.The effects of cycled versus noncycled lighting on growth and development in preterminfants[J].Infant Behav Dev, 1995, 18(1):87-95.