Impact of outpatient management on the short-term outcome of very preterm infant with brocopulmonary dysplasia.

doi:10.11852/zgetbjzz2016-24-08-22

Abstract

Abstract: Objective To prospectively evaluate the impact of discharge management on the short-term outcome of very preterm infants with bronchopulmonary dysplasia (BPD). Methods The preterm infants who were admitted in Neonatal Intensive Care Unit of the first Affiliated Hospital of Sun Yat-Sen University from January 2013 to October 2014 were enrolled.Their gestational age was<32 weeks and all of them survived ≥28 d.The very preterm infants were divided into BPD group and non-BPD group.All the infants received follow up and early interventions.Their growth parameters,neurodevelopment events and respiratory symptoms were evaluated regularly after discharge. Results Totally 76 preterm infants were enrolled and the morbidity of BPD was 51.3%.There was no death and cerebral palsy among these very preterm infants.Their growths in weight and length between BPD and non-BPD groups had no significant differences(P ≥0.05),while their growth in head circumference of BPD group was slower than that of non-BPD group(P<0.05).The incidences of pneumonia,wheezing and re-hospitalization in BPD group were significantly higher than those of non-BPD group(P<0.05). Conclusions Discharge management could improve the short-term outcome of very preterm infants with BPD.It could promote their growth and neurodevelopment without decreasing the incidence of respiratory symptoms after discharge.

Key words: outcome, brochopulmonary dysplasia, outpatient management, follow up, very preterm

摘要： 目的通过与非支气管肺发育不良(BPD)极早产儿进行对比,探讨院外综合管理对BPD极早产儿近期预后的影响。方法选取2013年1月-2014年10月于中山大学附属第一医院出生并收住新生儿重症监护室(NICU)、存活时间≥28 d的极早产儿为研究对象,按有无合并BPD分为BPD组及非BPD组。对患儿出院后均进行规范随访及早期干预,比较两组患儿体格和神经系统发育情况、呼吸道症状发生率和再住院次数。结果符合入选标准有76例极早产儿,其中BPD患儿39例,BPD发生率51.3%。两组均无死亡、失明及脑瘫患儿。BPD组纠正3、6月龄及12月龄时体重、身长完成追赶性生长比例与非BPD组相仿(P≥0.05),但头围的追赶性生长较非BPD组差(P<0.05)。BPD组合并肺炎次数、哮喘发作次数、再入院次数明显高于非BPD组(P<0.05)。结论院外综合管理可改善BPD极早产儿预后,有助于促进其追赶性生长及减少神经系统不良预后,达到非BPD极早产儿水平,但未能降低其呼吸道症状发生率。

关键词: 支气管肺发育不良, 院外管理, 随访, 极早产儿, 预后

CLC Number:

:R179

FENG Mei-mei,LIU Wang-kai,LI Xiao-yu,YU Mu-xue,ZHUANG Si-qi,LI Yi-juan.. Impact of outpatient management on the short-term outcome of very preterm infant with brocopulmonary dysplasia.[J]. journal1, 2016, 24(8): 859-862.

冯媚媚,刘王凯,李晓瑜,余慕雪,庄思齐,李易娟. 院外综合管理对支气管肺发育不良极早产儿近期预后的影响[J]. 中国儿童保健杂志, 2016, 24(8): 859-862.

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