微塑料对新生儿健康影响的研究

doi:10.11852/zgetbjzz2022-0429

中国儿童保健杂志 ›› 2023, Vol. 31 ›› Issue (4): 399-403.DOI: 10.11852/zgetbjzz2022-0429

微塑料对新生儿健康影响的研究

张雪怡, 张亚昱, 李佳

内蒙古医科大学附属医院新生儿科,内蒙古呼和浩特 010050

收稿日期:2022-04-07 修回日期:2022-06-07 发布日期:2023-04-18 出版日期:2023-04-10
通讯作者: 李佳,E-mail:19239383@qq.com;张亚昱,E-mail:sususanmusen@126.com
作者简介:张雪怡(1995-),女,内蒙古人,医师,硕士研究生在读,主要研究方向为新生儿营养。
基金资助:
2021年度内蒙古自治区高等学校科学研究项目(NJZZ21037)

Research progress in the impact of microplastics on newborn's health

ZHANG Xueyi, ZHANG Yayu, LI Jia

Department of Neonatology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia 010050, China

Received:2022-04-07 Revised:2022-06-07 Online:2023-04-10 Published:2023-04-18
Contact: LI Jia, E-mail:19239383@qq.com;ZHANG Yayu,E-mail:sususanmusen@126.com

摘要/Abstract

摘要： 塑料目前在全世界范围内广泛使用,自然条件下可降解为微塑料。微塑料广泛存在于空气、水及土壤中,通过呼吸道、消化道等途径进入生物体内,以物理堆积和化学方式损害健康。近年来,有关微塑料危害人类健康的研究日益增多,已经成为研究热点。随着研究的不断深入,发现微塑料与新生儿的健康联系紧密,并有可能成为新生儿生存质量的影响因素之一。但目前关于微塑料影响新生儿健康的报道较少,因此本文拟通过收集现有研究,对微塑料的接触途径及危害等进行综述。

关键词: 微塑料, 新生儿, 生存质量, 身体健康

Abstract: Plastics are now widely used around the world and can degrade into microplastics under natural conditions. Microplastics are widely found in air, water and soil, and enter into organisms through respiratory and digestive tracts, damaging health by physical accumulation and chemical means. In recent years, research on the harm that microplastics do on human health has been increasing and has become a research hotspot. As research continues, microplastics have been found to be strongly associated with the health of newborns and may be one of the factors influencing the quality of survival of newborns. However, there are few reports on the effects of microplastics on neonatal health, so this paper intends to review the exposure pathways and hazards of microplastics by collecting existing studies.

Key words: microplastics, neonates, quality of survival, good health

中图分类号:

R174
X503.1

张雪怡, 张亚昱, 李佳. 微塑料对新生儿健康影响的研究[J]. 中国儿童保健杂志, 2023, 31(4): 399-403.

ZHANG Xueyi, ZHANG Yayu, LI Jia. Research progress in the impact of microplastics on newborn's health[J]. Chinese Journal of Child Health Care, 2023, 31(4): 399-403.

参考文献

[1] Vizcaino E, Grimalt JO, Glomstad B, et al. Gestational weight gain and exposure of newborns to persistent organic pollutants[J]. Environ Health Perspect,2014,122(8):873-879.
[2] Hartmann NB, Huffer T, Thompson RC, et al. Are we speaking the same language? Recommendations for a definition and categorization framework for plastic debris[J]. Environ Sci Technol,2019,53(3):1039-1047.
[3] Street ME,Bernasconi S. Microplastics, environment and child health[J]. Ital J Pediatr,2021,47(1):75.
[4] Mohamed Nor NH, Kooi M, Diepens NJ, et al. Lifetime accumulation of microplastic in children and adults[J]. Environ Sci Technol,2021,55(8):5084-5096.
[5] Cox KD, Covernton GA, Davies HL, et al. Human consumption of microplastics[J]. Environ Sci Technol,2019,53(12):7068-7074.
[6] Li D, Shi Y, Yang L, et al. Microplastic release from the degradation of polypropylene feeding bottles during infant formula preparation[J]. Nature Food,2020,1(11):746-754.
[7] Soltani NS, Taylor MP, Wilson SP. Quantification and exposure assessment of microplastics in Australian indoor house dust[J]. Environ Pollut,2021,283:117064.
[8] Semmler-Behnke M, Kreyling WG, Schulz H, et al. Nanoparticle delivery in infant lungs[J]. Proc Natl Acad Sci U S A,2012,109(13):5092-5097.
[9] Fournier SB, D'Errico JN, Adler DS, et al. Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy[J]. Part Fibre Toxicol,2020,17(1):55.
[10] Ragusa A, Svelato A, Santacroce C, et al. Plasticenta:First evidence of microplastics in human placenta[J]. Environ Int,2021,146:106274.
[11] Kutralam-Muniasamy G, Pérez-Guevara F, Elizalde-Martínez I, et al. Branded milks - Are they immune from microplastics contamination?[J]. Sci Total Environ,2020,714:136823.
[12] Song K, Ding R, Sun C, et al. Microparticles and microplastics released from daily use of plastic feeding and water bottles and plastic injectors:Potential risks to infants and children in China[J]. Environ Sci Pollut Res Int,2021,28(42):59813-59820.
[13] Su Y, Hu X, Tang H, et al. Steam disinfection releases micro(nano)plastics from silicone-rubber baby teats as examined by optical photothermal infrared microspectroscopy[J]. Nature Nanotechnology,2022,17(1):76-85.
[14] Prüst M, Meijer J, Westerink RHS. The plastic brain:neurotoxicity of micro- and nanoplastics[J]. Part Fibre Toxicol,2020,17(1).doi:10.1186/s12989-020-00358-y.
[15] Hua T, Kiran S, Li Y, et al. Microplastics exposure affects neural development of human pluripotent stem cell-derived cortical spheroids[J]. J Hazard Mater,2022,435:128884.
[16] Li L, Xu Y, Li S, et al. Molecular modeling of nanoplastic transformations inalveolar fluid and impacts on the lung surfactant film[J]. J Hazard Mater,2022,427:127872.
[17] Shi W, Cao Y, Chai X, et al. Potential health risks of the interaction of microplastics and lung surfactant[J]. J Hazard Mater,2022,429:128109.
[18] Braun T, Ehrlich L, Henrich W, et al. Detection ofmicroplastic in human placenta and meconium in a clinical setting[J]. Pharmaceutics,2021,13(7).doi:10.3390/pharmaceutics13070921.
[19] Schwabl P, Koppel S, Konigshofer P, et al. Detection ofvarious microplastics in human stool:A prospective case series[J]. Ann Intern Med,2019,171(7):453-457.
[20] Lu L, Wan Z, Luo T, et al. Polystyrene microplastics induce gut microbiota dysbiosis and hepatic lipid metabolism disorder in mice[J]. Sci Total Environ,2018,631-632:449-458.
[21] Cheng W, Li X, Zhou Y, et al. Polystyrene microplastics induce hepatotoxicity and disrupt lipid metabolism in the liver organoids[J]. Sci Total Environ,2022,806:150328.
[22] Banerjee A, Billey L, McGarvey A, et al. Effects of polystyrene micro/nanoplastics on liver cells based on particle size, surface functionalization, concentration and exposure period[J]. Sci Total Environ,2022:155621.
[23] Huang T, Zhang W, Lin T, et al. Maternal exposure to polystyrene nanoplastics during gestation and lactation induces hepatic and testicular toxicity in male mouse offspring[J]. Food Chem Toxicol,2022,160:112803.
[24] Cai J, Zang X, Wu Z, et al. Translocation of transition metal oxide nanoparticles to breast milk and offspring:The necessity of bridging mother-offspring-integration toxicological assessments[J]. Environ Int,2019,133(Pt A):105153.
[25] Melnik E, Buzulukov Y, Demin V, et al. Transfer of silver nanoparticles through the placenta and breast milk during in vivo experiments on rats[J]. Acta naturae,2013,5(3):107-115.
[26] Tanwar V, Adelstein JM, Grimmer JA, et al. PM2.5 exposure in utero contributes to neonatal cardiac dysfunction in mice[J]. Environ Pollut,2017,230:116-124.
[27] Roshanzadeh A, Oyunbaatar NE, Ganjbakhsh SE, et al. Exposure to nanoplastics impairs collective contractility of neonatal cardiomyocytes under electrical synchronization[J]. Biomaterials,2021,278:121175.
[28] Li Z, Zhu S, Liu Q, et al. Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats[J].Environ Pollut,2020,265:115025.
[29] Bojic S, Falco MM, Stojkovic P, et al. Platform to study intracellular polystyrene nanoplastic pollution and clinical outcomes[J]. Stem Cells,2020,38(10):1321-1325.
[30] Lee H, Amarakoon D, Wei C, et al. Adverse effect of polystyrene microplastics (PS-MPs) on tube formation and viability of human umbilical vein endothelial cells[J]. Food Chem Toxicol,2021,154:112356.
[31] Hu J, Qin X, Zhang J, et al. Polystyrene microplastics disturb maternal-fetal immune balance and cause reproductive toxicity in pregnant mice[J]. Reprod Toxicol,2021,106:42-50.
[32] Haddadi A, Kessabi K, Boughammoura S, et al. Exposure to microplastics leads to a defective ovarian function and change in cytoskeleton protein expression in rat[J]. Environ Sci Pollut Res Int,2022,29(23):34594-34606.
[33] Chen Y, Chen K, Lin K, et al. The nephrotoxic potential of polystyrene microplastics at realistic environmental concentrations[J]. J Hazard Mater,2022,427:127871.

微塑料对新生儿健康影响的研究

Research progress in the impact of microplastics on newborn's health

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

[1]	韦萍, 韦霁珊, 黄旭华, 张宇星, 刘湘红, 何仲彪, 莫靖媛, 黄增帅, 玉群. 心脏听诊、血氧饱和度检测联合吸氧情况在广西新生儿先天性心脏病筛查中的应用[J]. 中国儿童保健杂志, 2024, 32(9): 1034-1039.
[2]	刘畅, 张立琴, 杜玮, 刘婷廷. 2023年美国儿科学会先天性甲状腺功能减低症筛查与管理指南解读[J]. 中国儿童保健杂志, 2024, 32(6): 637-642.
[3]	鲍成臻, 高丽丽, 韩历丽. 北京市青少年生存质量现状与健康认知和健康行为的关系[J]. 中国儿童保健杂志, 2024, 32(6): 687-691.
[4]	卢凌亚, 程薇, 吕兰秋. 宁波市2017—2021年儿童先心病流行特征和趋势研究[J]. 中国儿童保健杂志, 2024, 32(2): 202-207.
[5]	崔鹏源, 李贵平. 孟德尔随机化法探究新生儿高胆红素血症与抽动障碍的因果关联[J]. 中国儿童保健杂志, 2024, 32(10): 1116-1121.
[6]	滕云飞, 段钊, 张婷婷, 王惠萍, 乞艳华, 郭琳琼, 李小鹏. 脐膨出畸形胎儿的妊娠结局及发育随访[J]. 中国儿童保健杂志, 2024, 32(10): 1145-1148.
[7]	韦菊芳, 陈吉健. 2015—2021年南宁市西乡塘区新生儿低出生体重变化趋势及影响因素分析[J]. 中国儿童保健杂志, 2023, 31(7): 785-789.
[8]	刘维韦, 娄海琴, 付路, 代倩倩. 学龄前超重肥胖儿童生存质量现状及影响因素分析[J]. 中国儿童保健杂志, 2023, 31(4): 385-389.
[9]	张娟娟, 马金旗, 曾军安, 何阿玲. 新生儿遗传性出血性毛细血管扩张症1例并文献回顾[J]. 中国儿童保健杂志, 2023, 31(2): 225-228.
[10]	武童, 冀红. 高氧与未成熟脑损伤的研究进展[J]. 中国儿童保健杂志, 2023, 31(11): 1214-1218.
[11]	许安琪, 翟玲玲. 微塑料胎盘暴露现状及对胎儿影响的研究进展[J]. 中国儿童保健杂志, 2023, 31(11): 1235-1240.
[12]	张笃飞, 张湘云. 海南省2020年新生儿先天性心脏病的流行病学调查[J]. 中国儿童保健杂志, 2023, 31(1): 91-95.
[13]	王惠萍, 王莉, 高琼, 白铂亮, 马颖君. 极低出生体重坏死性小肠结肠炎患儿体格及神经发育的研究[J]. 中国儿童保健杂志, 2023, 31(1): 96-100.
[14]	袁源, 陈密. 脐带血miR-431表达水平与新生儿先天性听力障碍关系的研究[J]. 中国儿童保健杂志, 2023, 31(1): 101-104.
[15]	刘俐, 魏思萌, 姜忒. 新生儿营养与儿童早期发展[J]. 中国儿童保健杂志, 2022, 30(8): 879-883.