维生素及微量元素水平与孤独症谱系障碍相关性的研究进展

doi:10.11852/zgetbjzz2023-1194

摘要/Abstract

摘要： 孤独症谱系障碍(ASD)是一系列复杂的神经发育障碍性疾病,目前病因尚未明确。有研究表明ASD患儿体内维生素及微量元素含量存在异常,补充相应维生素及微量元素可以在一定程度上改善ASD患儿的临床症状,但具体机制尚不明确。本综述从维生素及微量元素的代谢和生理角度出发,整理了国内外关于维生素及微量元素与ASD的相关性研究,并探讨维生素及微量元素在ASD中的可能作用机制,以期为ASD的临床治疗提供新的视角和方向。

关键词: 孤独症谱系障碍, 维生素, 微量元素, 儿童

Abstract: Autism spectrum disorders (ASD) is a complex neurodevelopmental disorder, and its etiology remains unclear. Some studies have suggested that children with ASD may have abnormal levels of vitamins and trace elements in their bodies, and supplementing the corresponding vitamins and trace elements can improve the clinical symptoms of ASD children to some extent. However, the specific mechanisms are still unknown. From the metabolic and physiological perspectives of vitamins and trace elements,this review combs relevant researches from domestic and international sources on the correlation between ASD and vitamins and trace elements. It further discusses the potential mechanisms of how these vitamins and trace elements act in ASD, aiming to provide new perspectives and directions for the clinical treatment.

Key words: autism spectrum disorder, vitamins, micronutrient, children

中图分类号:

R749.94

赵婷婷, 孙昊, 张盼盼, 肖绪武. 维生素及微量元素水平与孤独症谱系障碍相关性的研究进展[J]. 中国儿童保健杂志, 2025, 33(1): 77-82.

ZHAO Tingting, SUN Hao, ZHANG Panpan, XIAO Xuwu. Association of vitamins and trace elements level with autism spectrum disorder[J]. Chinese Journal of Child Health Care, 2025, 33(1): 77-82.

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