Objective To understand the situation of pregnant women Perfluorinated compounds(PFCs) occupational exposure, and to analyze the effects of 0~1 years old infants' physical and mental development when their mother subjected to the influence of PFCs. Method Pilot investigation was used to select 0~1 years old infants who went to a place for examination, and to collect infants' physical and mental development status and their mother' situation of PFCs occupational exposure with a self-designed questionnaire and Denver Development Screen Test (DPST). Results The survey of women's career related to PFCs occupational exposure factor accounted for 7.4%.The difference of the infants' physical development index, whose mother engaged in the career related to printing, leather and its products or other career were statistically significant, but the difference of the infants' mental development index was not statistically significant(P＞0.05).However, the survey Results showed that there were 60% infants that assessment result of mental development was suspicious, and their mother engaged in the career related to clothing and textile;there were 50% infants that assessment result of mental development was suspicious, and their mother engaged in the career related to boiler and coal-fired. Conclusion Women of childbearing age should avoid contact with PFCs, and those who engaged in the career related to PFCs should keep away from the environment as soon as possible.