Objective To understand the proportion of allergen in eczema of children for providing foundation for prevention and treatment of eczema. Method Bioresonance technology allergy therapy was used to detect the allergen of eczema in children. Results A total of 1 538 children with eczema were detected,1 272(82.70%) patients,among them had positive food allergen test.653(42.46%) patients had positive inhaled allergen test.504(32.77%) patients had positive allergen test both in food test and inhaled test.Cereal(1 020,66.32%) was the most common allergen in food allergen,followed by milk,egg,sea food,nut,bean,food preservative,beef and lamb;Dust(340,22.11%) was the most common allergen in inhaled allergen,followed by mite,flower,animal fur,mould,waste gas,cigarettes,cooking oil fume.Among different aging groups,there were significant differences in the positive rates between food allergen group and inhaled allergen group(P<0.05).Food allergen was the main allergen in infant eczema,with the growth of the age,inhaled allergen was the main allergen in elder children eczema.Conclusion The inducing factor of eczema can be found out by the detection of allergen,which providing the foundation for the prevention and treatment of eczema.