Objective To investigate the clinical characteristics and the risk factors of cerebral palsy(CP) complicated with epilepsy. Methods A total of 522 children with CP(92 cases complicated with epilepsy and 430 cases non-complicated with epilepsy) were studied retrospectively,including the high risk factors and iconography.The clinical onset of epilepsy,the type of paralysis and level of mental development were also analyzed in 92 cases complicated with epilepsy. Results The incidence of 522 cases of children with cerebral palsy with epilepsy was 17.6%.The study demonstrated that the risk factors of CP complicated with epilepsy were low birth weight (χ²=6.564,P<0.05)and intracranial hemorrhage(χ²=11.797,P<0.05).There were no statistically significant differences between the two groups in preterm delivery,asphyxia,and pathologic jaundice.The imaging findings showed the encephalomalacia(χ²=5.250,P<0.05) and brain structure deformity (χ²=14.020,P<0.05) were predictive risk factors for epilepsy,while there was no statistically differences between cerebral hypoplasia and ventriculomegaly (P>0.05 ).The most common onset type of epilepsy was tonic-clonic seizures(44.5%),myoclonic seizures in second place(28.3%),followed by focal seizures(15.3%),infantile spasms(10.8%),one patients without typical attack(1.1%).97.7% children with CP complicated with epilepsy had different degrees of mental retardation.The highest incidence of epilepsy was quadriplegia(61.9%). Conclusion Children with low birth weight,intracranial hemorrhage,cerebral palsy with mental retardation and structural brain abnormalities should increase risks for epilepsy,clinical attention should be paid to.