Objective To investigate suitable management model of early intervention on the high-risk neonates in Shunyi district. Methods According to conveniences of children and hopes of parent,all high-risk neonates were divided into intervention management group and intervention control group,at the same time random selected 60 cases (n=60) of the normal children health examination in department of child health care as normal control group.All the babies were measured using Gesell developmental scale when they were one year old;and compared before and after the standardize management:high-risk creates file rate,follow-up rate in 6 and 12 months old. Results In addition to the normal control group and management group comparison,in the big movement,fine movement and average development quotient,differences were not statistically significant (P>0.05),and the rest comparisons differences of the every two two groups were statistically significant (P<0.05);the comparison before and after the standardize the management:after standard management,high-risk neonates creates file rate,6 months,and 12 months of follow-up rate,the differences were statistically significant (P<0.05). Conclusion System standard management of high-risk is important way to improve its filing rate,follow-up rate and the intervention effect.