Objective To explore the impact of TORCH intrauterine infection on neonatal behavioral and neurological development. Methods Choosing gestational age 37~42 weeks,umbilical cord blood or peripheral blood check TORCH series antibody one or more IgM(+),the mother in the prenatal screening or intrapartum monitoring TORCH series antibody one or more same pathogen IgM(+) of newborn as the infection team,while mother and neonatal umbilical cord blood and peripheral blood TORCH infection were checked all negative of 100 cases of neonatal as control group,two groups of newborn babies born in 48~72 hours,12~14 days,26~28 days were examined of NBNA score. Results Neonatal rubella virus,cytomegalovirus,herpes virus,toxoplasma infection rate had statistics significant differences (P<0.05),including cytomegalovirus infection rate was up to 1.48%,the lowest toxoplasma infection rate was 0.12%;Each time rubella virus and cytomegalovirus infection group of neonatal NBNA scores were lower than those of the control group (P<0.05),toxoplasma and herpes virus infection group of neonatal NBNA score and control group had no significant difference (P>0.05),NBNA score had no significant difference among the infection groups(P>0.05).The same infection group,neonatal NBNA scores in three periods had the significant differences (P<0.05). Conclusion TORCH intrauterine infection will affect the development of neonatal behavioral neurological development.