Objective To explore the evolution of flash visual evoked potentials (FVEP) in preterm infants from 1 to 36 months,and compare to the full-term. Method Using the Viking-Ⅳ visual electrophysiological testing device,the latency and amplitude values of the P2 main wave on FVEPs were recorded in infants longitudinally at 1,3,6,9,12,18,24 and 36 months. Results The trends of FVEPs were similar in the three groups of children,the latency of the P2 showed a significant decrease along with the age,but the amplitude had no difference.The latency of the P2 was more significantly delayed in VLBW group than in full-term group from 1 to 24 months,but there was no significant difference at 36 months; the LBW group showed the latency of the P2 wave was significantly delayed compared with the full-term group,only in 1~6 months. Conclusions Premature and LBW have the negative influence on the development of children's visual system,especially for VLBW.The follow-up evaluation of visual function state of this preterm group should be strengthened in school-age period.
Key words
low birth weight /
flash visual evoked potentials /
longitudinal study /
preterm infants
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References
[1] Madan A,Jan JE,Good WV.Visual development in preterm infants[J].Developmental Medicine and Child Neurology,2005,47(4):276-280.
[2] Shepherd AJ,Saunders KJ,McCulloch DL,et al.Prognostic value of flash visual evoked potentials in preterm infants[J].Dev Med Child Neurol,1999,41(1):9-15.
[3] Moskowitz A,Sokol S.Development changes in the human visual system as reflected by the latency of the pattern reversal VEP[J].Elect roencephalogr Clin Neurophysiol,1983,56(1):12-15.
[4] Lenassi E,Likar K,Branka SK,et al.VEP maturation and visual acuity in infants and preschool children[J].Documenta Ophthalmologica,2008,117(2):111-120.
[5] 冯菁菁,王婷雪,王卫平,等.6~24月龄婴幼儿闪光视觉诱发电位纵向随访[J].中国儿童保健杂志,2010,18(02):113-115.
[6] Ruberto G,Redaelli C,Cataldo S.Compared progression of Visual evoked potentials in preterm and term newborns[J].Journal Francals Ophtalmologie,2004,27(9):1032-1038.
[7] Spierer A,Royzman Z,Kuint J.Visual acuity in premature infants[J].Ophthalmologica,2004,21(8):115-118.
[8] Feng JJ,Wang TX,Yang CH,et al.Flash visual evoked potentials at 2-year-old infants with different birth weights[J].World Journal of Pediatrics,2010,6(2):163-168.
[9] Atkinson J,Anker S,Rae S,et al.Cortical visual evoked potentials in very low birth weight premature infants[J].Arch Dis Child Fetal Neonatal Ed,2002,86:28-31.
[10] Laura C,Elena P,Alessandro S,et al.Acceleration of visual system development by environmental enrichment[J].The Journal of Neuroscience,2004,24(20):4840-4848.