【Objective】 To explore the management pattern applys to high risk infants in community screening,monitoring and intervention. 【Methods】 High risk infants monitoring network was established.Management program included screening,registering,monitoring,referral and rehabilitation.When children were born,community physicians were responsible for there screening,monitoring and referral.340 high risk infants were divided into system intervention group and non system intervention group,their neuromotor development and intellectual development were regular assessed.T-test and χ²-test were used for statistical analysis. 【Results】 High risk infants community management coverage was up to 94.44%.System intervention group developmental quotient was obvious higher and neuromotor abnormalities was significantly lower than non system intervention group. 【Conclusion】 The key to improve children's psychological development and reduce cerebral palsy and intellectual disability was to establish high risk infants community monitoring network and formulate intervention system apply to community.