【Objective】 To investigate the clinical application value of qualitative assessment of general movements for high risk infants follow-up. 【Methods】 253 high risk infants follow-up in rehabilitation department were accepted the qualitative assessment of general movements respectively in the twist movements period and fidgety movements period.Motor developmental outcome was defined by clinical diagnosis and Peabody Motor Develoment Scale assessment after 12-month-age(corrected age of premature infants).Its application value was analysed. 【Results】 The monotonicity of twist movements period assessment value was not high,only the spasm -synchronous movements had prediction value of synchronicity.The predictive validity of cerebral palsy was as follows:sensitivity 72%,specificity 99%,positive predictive value 95%,and negative predictive value 92%.Fidgety movements lack in the irregular movement phase had the high predictive value of fidgety movements.The predictive validity of cerebral palsy was as follows:sensitivity 100%,specificity 96%,positive predictive value 86%,and negative predictive value 100%. 【Conclusions】 The spasm-synchronous movements of twist movements period have prediction value of synchronicity.Fidgety movements assessment for high risk infants have predictive value of motor developmental outcome,especially with cerebral palsy,clinical use should be extended in high risk infants follow-up as evaluation tool.