Longitudinal growth and serum IGF-1/IGFBP3 level in simple obese school children

XIONG Xi; LIAO Ba-gen

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Chinese Journal of Child Health Care ›› 2012, Vol. 20 ›› Issue (6) : 547-550.

Longitudinal growth and serum IGF-1/IGFBP3 level in simple obese school children

XIONG Xi¹,LIAO Ba-gen²

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Abstract

【Objective】 To investigate the longitudinal growth and serum IGF-1/IGFBP3 levels in simple obese children. 【Methods】 Height/weight data were collected in a health examination cohort from ages 7~11 years old in two primary schools in Guangzhou.According to body mass index (BMI) classification references for normal weight and obesity,31 (20 boys and 11 girls) sustained simple obese (SSO) children and 42 (20 boys and 22 girls) gender and mid-parental height-matched sustained normal weight (SNW) children were screened to analyze the longitudinal changes of height from 7 to 11 years old and to determine the fast serum IGF-1/IGFBP3 levels at 11 years old. 【Results】 The height was taller in SSO boys than in matched SNW boys at each corresponding age,and basal IGF-1/IGFBP3 levels were also higher in SSO boys than in matched SNW boys at 11 years old (P<0.05).There was no significant difference in height between SSO and matched SNW girls,nor did in basal IGF-1/IGFBP3 between SSO girls and matched SNW girls at 11 years old. 【Conclusion】 Simple obese prepubertal or pubertal children have normal linear growth or accelerated linear growth with normal or increased basal serum IGF-1/IGFBP3 levels correspondingly.

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obesity / growth / IGF-1

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XIONG Xi,LIAO Ba-gen. Longitudinal growth and serum IGF-1/IGFBP3 level in simple obese school children[J]. Chinese Journal of Child Health Care. 2012, 20(6): 547-550

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