【Objective】 To investigate the incidence and prognosis of infants with congenital heart disease (CHD). 【Methods】 There were 8 259 cases about the young children who were full-term live births born in Ningbo Haishu district From 2008 to 2010.221 cases were diagnosed by echocardiography in infants with congenital heart disease,they were regular follow-up tracked. 【Results】 The incidence of infants with congenital heart among the top four respectively were the ventricular septal defect,(accounting for 24.89%),patent foramen ovale (accounting for 22.62%),atrial septal defect with patent ductus arteriosus (accounting for 13.57%),arterial ductus closure and patent foramen ovale (accounting for 13.57%);221 cases of congenital heart disease were diagnosed before their first birthday. 【Conclusion】 Congenital heart disease is an important public health problems,carry out monitoring and follow-up congenital heart disease,could improve quality of life of infants and young children.