[1] Missler M,Sudhof TC.Neurexins:three genes and 1001 products[J].Trends Genet,1998,14(1):20-26.
[2] Bishop Dorothy VM,Scerif G.Klinefelter syndrome as a window on the aetiology of language and communication impairments in children:the neuroligin-neurexin hypothesis[J].Acta Paediatr,2011,100(6):903-907.
[3] Frederique V,Stephane J,Nils B.Neuroligin 2 is exclusively localized to inhibitory synapses[J].Eur J Cell Biol,2004,83(9):449-456.
[4] Owens DF,Kriegstein AR.Is there more to GABA than synaptic inhibition[J].Nat Rew Neurosci,2002,3(9):715-727.
[5] Lawrence YA,Kemper TL,Bauman ML,et al.Parvalbumin-,calbindin-,and calretinin-immunoreactive hippocampal interneuron density in autism[J].Acta Neurol Scand,2010,121(2):99-108.
[6] Rubenstein JLR,Merzenich MM.Model of autism:increased ratio of excitation/inhibition in key neural systems[J].Genes Brain Behav,2003,2(5):255-267.
[7] Wisniowiecka KB,Nesteruk M,Peters SU,et al.Intragenic rearrangements in NRXN1 in three families with autism spectrum disorder,developmental delay,and speech delay[J].Am J Med Genet Bneuropsychiatr Genet,2010,135B(5):983-993. [8] Kim HG,Kishikawa S,Higgins AW,et al.Disruption of neurexin 1associated with autism spectrum disorder[J].Am J Hum Genet,2008,82(1):199-207.
[9] Zahir FR,Baross A,Delaney AD,et al.A patient with vertebral,cognitive and behavioural abnormalities and a de novo deletion of NRXN1a[J].J Med Genet,2008,45(4):239-243.
[10] Bucan M,Abrahams BS,Wang K,et al.Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes[J].Plos Genet,2009,5(6):e1000536.
[11] Feng J,Schroer R,Yan J,et al.High frequency of neurexin 1beta signal peptide structural variants in patients with autism[J].Neurosci Lett,2006,409(1):10-13.
[12] Yan J,Noltner K,Feng J,et al.Neurexin 1alpha structural variants associated with autism[J].Neurosci Lett,2008,438(3):368-370.
[13] Wang K,Zhang H,Ma D,et al.Common genetic variants on 5p14.1 associate with autism spectrum disorders[J].Nature,2009,459(7246):528-533.
[14] Wang L,Jia M,Yue W,et al.Association of the ENGRAILED 2(EN2)gene with autism in Chinese Han population[J].Am J Med Genet B Neuropsychiatr Genet,2008,147B(4):434-438.
[15] Gauthier J,Siddiqui TJ,Huashan P,et al.Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia[J].Hum Genet,2011,130(4):563-573.
[16] Etherton MR,Blaiss CA,Powell Craig M,et al.Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments[J].Proc Natl Acad Sci USA,2009,106(42):17998-18003.
[17] Blundell J,Blaiss CA,Etherton MR,et al.Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior[J].J Neurosci,2010,30(6):2115-2129.
[18] Biswas S,Russell RJ,Jackson CJ,et al.Bridging the synaptic gap:neuroligins and neurexin I in Apis mellifera[J].Plos One,2008,3(10):e3542.
[19] Biswas S,Reinhard J,Oakeshott J,et al.Sensory regulation of neuroligins and neurexin I in the honeybee brain[J].Plos One,2010,5(2):e9133.
[20] Rubenstein JL,Merzenich MM.Model of autism:Increased ratio ofexcitation/inhibition in key neural systems[J].Genes Brain Behav,2003,2:255-267.