【Objective】 To find out the influences of high blood lead level on visual acuity,stereoacuity,visual evoked potentials in children. 【Method】 172 children aged 4 to 10 were randomly selected and their serum concentration of lead were detected.They were divided into normal blood lead group and high blood lead group by the blood lead level. 【Results】 The difference of cases with abnormal corrected visual acuity between high blood lead group and normal blood lead group was statistically significant(P<0.01).P100 latency was significantly delayed and the difference of P100 latency and stereoacuity were statistically significant between two groups(P<0.05).P100 amplitudes did not differ significantly from the normal group(P>0.05). 【Conclusions】 High blood lead level has bad influence on visual acuity,stereoacuity,visual evoked potentials in children.More attention should be paid to the prevention of the lead pollution and the abnormal development of visual function.
Key words
lead /
visual acuity /
stereoacuity /
visual evoked potential
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
References
[1] 中华人民共和国卫生部.《儿童高铅血症和铅中毒预防指南》及《儿童高铅血症和铅中毒分级和处理原则(试行)》[S].卫妇社发[ 2006]51号,2006.
[2] 赵堪兴,杨培增.眼科学[M].7版.北京:人民卫生出版社,2011:264-265.
[3] 叶葶葶.预防医学[M].3版.北京:人民卫生出版社,2000:36-39.
[4] 胡亚美,江载芳.实用儿科学[M].7版.北京:人民卫生出版社,2002:2448-2453.
[5] 王光霁,崔浩.双眼视觉学[M].北京:人民卫生出版社,2004:150-152.
[6] Parker AJ.Binocular depth perception and the cerebral cortex[J].Nat Rev Neurosci,2007,8(5):379-391.
[7] 刘紫萍.预防医学[M].北京:高等教育出版社,2009:48-49.
[8] Pojda-Wilczek D,Herba E,Schneiberg B.Visual evoked potentials in children with high blood lead level[J].Klin Oczna,2005,107(10-12):658-661.
[9] Altmann L,Sveinsson K,Krmer U.Visual functions in 6-year-old children in relation to lead and mercury levels[J].Neurotoxicol Teratol,1998,20(1):9-17.
[10] Pojda-Wilczek D,Herba E,Schneiberg B.Visual evoked potentials in children cured with sodium-calcium versenate because of high blood lead level-the prospective study[J].Klin Oczna,2005,107(10-12):662-664.