【Objective】 To increase the appreciation of manifestation through the analysis of clinical features in children with Asperger syndrome. 【Method】 Information on chief complaints, clinical manifestation, family backgrounds, gestational and perinatal factors, and the Wechsler intelligence quotient results of patients with Asperger syndrome from November 2006 to February 2011 were studied. 【Results】 1)19 cases were diagnosed with Asperger syndrome at the average age of (80.7±21.4) months and a male to female ratio of 18:1; 2) The most common manifestations were poor peer relationship (100%), attention deficit (94.7%), difficulty to comprehend semantics (89.5%), restricted interests (84.2%), clumsiness (78.9%), hyperactivity (78.9%), deficiency in nonverbal communication (73.7%), repetitive and stereotyped patterns of behaviors (73.7%);3) There were similar problems in several children's fathers, and most parents especially fathers had high degree;4) Verbal IQ was often higher than performance IQ in Wechsler intelligence. 【Conclusion】 Manifestations of Asperger syndrome are not only specific but also occult, the clinical recognition of these features is important for early identification and diagnosis.