【Objective】 To evaluate the effect of integrated health-care interventions for children under 5 years old in target rural counties of Shaanxi Province and to provide experiences and lessons for following projects. 【Methods】 From 2007 to 2010, a project focusing on maternal and child health care was launched in targeted rural areas of Shaanxi Province, with integrated interventions. Together with using multistage, stratified, randomly, non-probability sampling, two cross-sectional surveys were conducted in 2006 and 2010, and a before/after intervention design was used to assess the effectiveness of the integrated interventions by changes in children's growth and development, health outcome, guardians' health-related knowledge and behavior. 【Results】 The decrease in the stunting rate was more than 50% after intervention(6.9% to 3.4%, P<0.01). The rate of anemia was still high and also little effect had been shown in reduction of both two-week prevalence of suspected pneumonia and two-week prevalence of diarrhea(P>0.05). However, there was significant improvement in health awareness and behavior among caregivers, especially the rate of professional care-seeking when either of the disease occurred increased dramatically to more than 85%. 【Conclusions】 This project, to some extent, has promoted the health of children under 5 and the level of health care, but little effect showed in the reduction of anemia, suspected pneumonia and diarrhea. So it is still urgent to seek more specific and targeted interventions fighting against such problems and to improve intensity of interventions as well.