【Objective】 To analyse the risk of amblyopia among 0~2 years old premature infants by Suresight screening. 【Method】 Refraction was measured by Suresight screening at corrected age of 6 months,9 months,12 months,18 months and 24 months old in 264 preterm infants without retinopathy between December 2009 to December 2010. 50 full term infants age-matched were also included in the study as control groups. We analysed the risk of amblyopia in preterm infants with the high-risk and suspicious criterion established by suresight screening in our pre-study. 【Results】 Higher incidence of moderate and high-dgree hyperopia、moderate and high-dgree astigmatism、anisometropia were found on preterm infants than in age-matched full term infants. Also higher incidence of high-risk and suspicious children of amblyopia were found on preterm infants,especially at 6 months aged. 【Conclusions】 The risk of amblyopia is higher in premature infants.It suggests that vision screening should be performed at the age of 6 months old in preterm infants and vision monitoring should be given in their childhood,which will help to correct refractive error early and decrease the rate of amblyopia.