Objective To evaluate the effectiveness of the integrated care model for infants and toddlers with autism spectrum disorder (ASD) in childcare institutions in Wenzhou, and to explore the integrated care model guided by medical-childcare integration, so as to provide reference for early intervention of ASD children. Methods A retrospective single-group pretest-posttest study was conducted. Twelve infants and toddlers with ASD who received integrated care services at Wenzhou Mibao Childcare Center were enrolled in this study from November 2021 to December 2025. An integrated service system encompassing screening, assessment, intervention, and follow-up was established. This system integrated professional rehabilitation training into daily nursery care routines through four pathways: medical-rehabilitation-childcare linkage, a dynamic assessment-intervention cycle, integration of intervention into daily childcare routines, and collaborative home-childcare-medical support. All participants received integrated care for at least 6 months.The Chinese (Hong Kong) Version of Psychoeducational Profile-Third Edition (CPEP-3) was used for assessment within 1 month after enrollment and every 3 months thereafter. Paired t tests and Wilcoxon signed-rank tests were used for comparative analyses. Results After integrated care, most CPEP-3 domain scores increased compared with baseline. Statistically significant differences were observed in 14 domains (P<0.05) , such as communication, motor function, social interaction, cognition, and language-related domains, whereas no significant differences were observed in personal self-care or adaptive behavior(P>0.05). Conclusions Guided by the medical-childcare integration model, the integrated care model in childcare institutions significantly enhances communication, social interaction, cognition, language, and motor development in infants and toddlers with ASD. This model offers a practical and potentially scalable framework for implementing comprehensive early intervention in childcare settings.
Key words
autism spectrum disorder /
medical-childcare integration /
integrated care /
childcare
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References
[1] 达振强,汪玉风,汪利霞,等. 基于全球疾病负担大数据的中国孤独症谱系障碍患病现状及趋势分析[J].兰州大学学报(医学版),2022, 48(5): 38-44.
Da ZQ, Wang YF, Wang LX, et al. Prevalence and trend analysis of autism spectrum disorders in China based on the big data of the Global Burden of Disease[J].J Lanzhou Univ (Med Sci), 2022, 48(5): 38-44.(in Chinese)
[2] Dawson G, Bernier R. A quarter century of progress on the early detection and treatment of autism spectrum disorder[J].Dev Psychopathol, 2013, 25(4pt2): 1455-1472.
[3] Lord C, Charman T, Havdahl A, et al. The Lancet Commission on the future of care and clinical research in autism[J]. Lancet, 2022, 399(10321): 271-334.
[4] Reichow B,Barton EE, Boyd BA, et al. Early intensive behavioral intervention (EIBI) for young children with autism spectrum disorders (ASD)[J]. Cochrane Database Syst Rev, 2012,10:CD009260.
[5] 李廷玉,韦秋宏,李燕,等. 养育照护融合家庭干预模式用于孤独症谱系障碍的实践与展望[J]. 中国儿童保健杂志,2024, 32(9): 937-940.
Li TY,Wei QH,Li Y,et al.Practice and prospects of integrating nurturing care and family interventions for autism spectrum disorder[J]. Chin J Child Health Care, 2024,32(9): 937-940.(in Chinese)
[6] Ge D, Wei H, Wang Y, et al. Effectiveness of caregiver-mediated intervention:A pilot study for children with neurodevelopmental disorders[J]. Prim Health Care Res Dev, 2022, 23: e63.
[7] Black MH, Kuzminski R, Wang J, et al. Experiences of friendships for individuals on the autism spectrum: A scoping review[J]. Rev J Autism Dev Disord, 2024, 11(1): 184-209.
[8] Miller LE, Dai YG, Fein DA, et al. Characteristics of toddlers with early versus later diagnosis of autism spectrum disorder[J]. Autism, 2021, 25(2): 416-428.
[9] Garfinkle AN, Schwartz IS. Peer imitation: Increasing social interactions in children with autism and other developmental disabilities in inclusive preschool classrooms[J]. Top Early Child Spec Educ, 2002, 22(1): 26-38.
[10] Katz E, Girolametto L. Peer-mediated intervention for preschoolers with ASD implemented in early childhood education settings[J]. Top Early Child Spec Educ, 2013, 33(3): 133-143.
[11] Salomone E, Settanni M, McConachie H, et al. Pilotrandomized controlled trial of the WHO caregiver skills training in public health services in Italy[J]. J Autism Dev Disord, 2022, 52(10): 4286-4300.
[12] 刘宇洁, 乌云高娃, 单银雪, 等. 融合教育中孤独症幼儿社会情感能力发展干预个案研究[J]. 北京教育学院学报, 2024, 38(3): 38-48.
Liu YJ, Wuyun GW, Shan YX, et al. A case study of intervention on social and emotional competence of children with ASD in inclusive education[J]. J Beijing Inst Educ, 2024, 38(3): 38-48. (in Chinese)
[13] Rice D, Barone SJr. Critical periods of vulnerability for the developing nervous system: Evidence from humans and animal models[J].Environ Health Perspect, 2000, 108: 511-533.
[14] Zhao J, Zhang X, Lu Y, et al. Virtual reality technology enhances the cognitive and social communication of children with autism spectrum disorder[J].Front Public Health, 2022, 10: 1029392.
[15] 关宏岩, 童梅玲. 特殊需求儿童养育照护的多维支持系统[J]. 中国儿童保健杂志, 2026, 34(5):478-484.
Guan HY, Tong ML. Multidimensional nurturing care support system for children with special needs[J]. Chin J Child Health Care, 2026, 34(5):478-484.(in Chinese)
[16] Wong CS. A play and joint attention intervention for teachers of young children with autism: A randomized controlled pilot study[J]. Autism, 2013, 17(3): 340-357.
[17] 中国妇幼保健协会托幼机构儿童保健专业委员会,中国妇幼保健协会婴幼儿养育照护专业委员会,中国妇幼健康研究会婴幼儿养育照护专业委员会,等.托育机构特殊健康需求婴幼儿养育照护专家共识[J].中国儿童保健杂志,2026,34(5):465-472.
Child Health Care in Nursery Institutions Committee, Chinese Maternal and Child Health Association; Infants and Toddlers Nurturing Care Committee, Chinese Maternal and Child Health Association; Infants and Toddlers Nurturing Care Committee, Chinese Maternal and Child Health Research Association, et al. Expert consensus on the nurturing care of infants and young children with special health needs in nursery institutions[J].Chin J Child Health Care,2026,34(5):465-472.(in Chinese)
[18] Freeman SFN. Early childhood inclusion: Focus on change[J]. Am J Ment Retard, 2003, 108(6): 435-436.
[19] UNICEF, WHO. Nurturing care for children with developmental delays and disabilities: thematic brief[EB/OL].(2026-03-02)[2026-03-26].https://www.who.int/publications/i/item/B09617