Characteristics of speech evoked auditory brainstem response in 120 preschool children

CHEN Bilan; LIU Panting; SUN Yuying; YU Xinyue; ZHOU Jia; LI Tingyu; XU Yaqin; MENG Liping; ZHANG Lei; QIAN Jun; CHI Xia; HONG Qin

doi:10.11852/zgetbjzz2024-1410

PDF(644 KB)

Chinese Journal of Child Health Care ›› 2025, Vol. 33 ›› Issue (11) : 1256-1260. DOI: 10.11852/zgetbjzz2024-1410

Clinical Research

Characteristics of speech evoked auditory brainstem response in 120 preschool children

CHEN Bilan^1,2, LIU Panting^1,3, SUN Yuying⁴, YU Xinyue², ZHOU Jia⁴, LI Tingyu²,XU Yaqin¹, MENG Liping¹, ZHANG Lei¹,QIAN Jun¹, CHI Xia^1,3, HONG Qin^1,3

Author information +

History +

Abstract

Objective To analyze the characteristics and influencing factors of speech-evoked auditory brainstem response (speech-ABR) in typically developed preschool children of different ages and genders, and to understand the development of auditory processing abilities in this population. Methods A total of 120 typically developed preschool children participating in the Nanjing norm study of the Preschool Auditory Processing Assessment Scale in August 2021 were selected for speech-ABR testing.Age and gender differences in speech-ABR parameters, as well as their influencing factors, were analyzed. Results 1) Statistically significant differences in the amplitude of the C-wave were observed among the 4-, 5-, and 6-year-old groups (H=6.950, P<0.05).Post-hoc pairwise comparisons revealed a significant difference between the 5- and 6-year-old groups (P=0.012).2) Boys exhibited prolonged latencies in waves V (Z=3.449), A (Z=2.845), D (Z = 2.111), F (Z=3.450), and O (Z=2.856) compared to girls (P<0.05).Wave amplitudes showed no significant gender-based differences (P>0.05).3) Stepwise multiple linear regression analysis indicated that male gender was associated with longer V-wave latency (β=0.290).Maternal pregnancy age at 25-29 years old (reference:≥35 years old) was associated with shorter V-wave latency (β =-0.219).Preterm birth<37 weeks (reference:≥37 weeks) was associated with shorter C-wave latency (β=-0.254).Higher maternal education level of bachelor′s degree or above (reference: college-educated group) was associated with greater V-wave amplitude (β =-0.200) (all P<0.05). Conclusions Speech-ABR responses in preschool children show significant gender-based differences, with minimal age-related variations.Maternal age at pregnancy, gestational age, and maternal education level may influence brainstem encoding abilities.

Key words

speech evoked auditory brainstem response / preschool children / gender difference / auditory processing

Cite this article

EndNote

Ris (Procite)

Bibtex

Download Citations

CHEN Bilan, LIU Panting, SUN Yuying, YU Xinyue, ZHOU Jia, LI Tingyu,XU Yaqin, MENG Liping, ZHANG Lei,QIAN Jun, CHI Xia, HONG Qin. Characteristics of speech evoked auditory brainstem response in 120 preschool children[J]. Chinese Journal of Child Health Care. 2025, 33(11): 1256-1260 https://doi.org/10.11852/zgetbjzz2024-1410

References

[1] Basoz BM, Guler N, Kuru E, et al.Speech auditory brainstem response in audiological practice: A systematic review[J].Eur Arch Otorhinolaryngol, 2023, 280(5): 2099-2118.
[2] Liu P, Lin H, Xiao Z, et al.The development, validity, reliability, and norm of a Preschool Auditory Processing Assessment Scale in China[J].Res Dev Disabil, 2022, 128: 104272.
[3] Moore JK, Linthicum FH.The human auditory system: A timeline of development[J].Int J Audiol, 2007, 46(9): 460-478.
[4] Moore JK, Ponton CW, Eggermont JJ, et al.Perinatal maturation of the auditory brain stem response: Changes in path length and conduction velocity.Ear Hear, 1996, 17(5): 411-418.
[5] Stollman MH, van Velzen EC, Simkens HM, et al.Development of auditory processing in 6-12-year-old children: A longitudinal study[J].Int J Audiol, 2004, 43(1): 34-44.
[6] Chen J, Liang C, Wei Z, et al.Atypical longitudinal development of speech-evoked auditory brainstem response in preschool children with autism spectrum disorders[J].Autism Res, 2019, 12(7): 1022-1031.
[7] Kirbac A, Turkyilmaz MD, Yağc1oglu S.Gender effects on binaural speech auditory brainstem response[J].J Int Adv Otol, 2022, 18(2): 125-130.
[8] Højen A, Schmidt ASM, Møller IS, et al.Unequal home literacy environments between preschool-age boys and girls predict unequal language and preliteracy outcomes[J].Acta Psychol, 2022, 230: 103716.
[9] Bölte S, Neufeld J, Marschik PB, et al.Sex and gender in neurodevelopmental conditions[J].Nat Rev Neurol, 2023, 19(3): 136-159.
[10] Stein J.The magnocellular theory of developmental dyslexia[J].Dyslexia, 2001, 7(1): 12-36.
[11] Guo N, Si X, Zhang Y, et al.Speech frequency-following response in human auditory cortex is more than a simple tracking[J].Neuroimage, 2021, 226: 117545.
[12] Chung WL, Bidelman GM.Mandarin-speaking preschoolers′ pitch discrimination, prosodic and phonological awareness, and their relation to receptive vocabulary and reading abilities[J].Read Writ, 2021, 34(2): 337-353.
[13] MacLean J, Stirn J, Sisson A, et al.Short- and long-term neuroplasticity interact during the perceptual learning of concurrent speech[J].Cereb Cortex, 2024, 34(2): bhad543.
[14] 李曼珊,马兰芳,宋海霞, 等.不同年龄段妊娠并发症/合并症及妊娠结局的分析[J].贵州医药, 2021,45(10):1557-1559.
Li MS, Ma LF, Song HX, et al.Analysis of pregnancy complications/comorbidities and pregnancy outcomes at different ages[J].Guizhou Med J, 2021,45(10):1557-1559.(in Chinese)
[15] Lean SC, Heazell AEP, Dilworth MR, et al.Placental dysfunction underlies increased risk of fetal growth restriction and stillbirth in advanced maternal age women[J].Sci Rep, 2017, 7(1): 9677.
[16] Ribas-Prats T, Arenillas-Alcón S, Lip-Sosa DL, et al.Deficient neural encoding of speech sounds in term neonates born after fetal growth restriction[J].Developmental Sci, 2022, 25(3): e13189.
[17] Coughlan S, Quigley J, Nixon E.Parent-infant conversations are differentially associated with the development of preterm- and term-born infants[J].J Exp Child Psychol, 2024, 239: 105809.
[18] Monson BB, Ambrose SE, Gaede C, et al.Language exposure for preterm infants is reduced relative to fetuses[J].J Pediatr, 2023, 262: 113344.
[19] Almadhoob A, Ohlsson A.Sound reduction management in the neonatal intensive care unit for preterm or very low birth weight infants[J].Cochrane Db Syst Rev, 2015, 1: CD010333.
[20] Di Fiore JM, Liu G, Loparo KA, et al.The effect of early postnatal auditory stimulation on outcomes in preterm infants[J].Pediatr Res, 2024, 96(6): 1389-1396.
[21] Romeo RR, Uchida L, Christodoulou JA.Socioeconomic status and reading outcomes: Neurobiological and behavioral correlates[J].New Dir Child Adolesc Dev, 2022, 2022(183-184): 57-70.