Objective To investigate the current status of developmental coordination disorder (DCD) among preschool children in Wujiang District, Suzhou City, to analyze its influencing factors, and to establish and validate a nomogram prediction model. Methods From September 2023 to January 2024, 341 preschool children in Wujiang District, Suzhou City, were randomly selected as the modeling set. From February to April 2024, 145 preschool children were randomly selected as the validation set. The Movement Assessment Battery for Children-2 (MABC-2) was used for screening, and the Developmental Coordination Disorder Questionnaire (DCDQ) was administered for surveys. The scores of MABC-2 dimensions and DCDQ were compared across different genders and age groups. Univariate and multivariate Logistic regression analyses were conducted to identify factors influencing DCD in preschool children. A nomogram prediction model was constructed, and receiver operating characteristic (ROC) curves and calibration curves were plotted to evaluate the discrimination and consistency of the model in internal (modeling set) and external (validation set) validation. Results Girls scored higher in manual dexterity but lower in aiming and catching compared to boys (t=2.811, 5.384, P<0.05). Girls and 6-year-old children scored higher in motor control, fine motor/writing abilities, and general coordination compared to boys (t=2.860, 5.775, 3.801) and 5-year-old children (t=4.372, 3.099, 2.679, P<0.05). Among the 341 preschool children in the modeling set, 31 cases of DCD were detected, yielding a detection rate of 9.09%. Independent risk factors for DCD included male gender (OR=2.072), father's education level of high school or below (OR=2.176), mother's education level of high school or below (OR=2.088), family annual income of <50 000 yuan (OR=2.551), and housing area of <75 m2 (OR=5.138, P<0.05). In the nomogram model, housing area was the most influential factor (99.8 points), followed by family income (59.2 points), father's education level (48.8 points), mother's education level (45.5 points), and gender (44.0 points). The area under the ROC curve (AUC) for internal validation (modeling set) was 0.789 (95%CI: 0.691 - 0.878), indicating good discrimination. The Hosmer-Lemeshow goodness-of-fit test yielded a value of 4.202 (P=0.838), indicating good consistency. For external validation (validation set), the AUC was 0.737 (95%CI: 0.676 - 0.853), with good discrimination, and the Hosmer-Lemeshow goodness-of-fit test yielded a value of 6.782 (P=0.624), indicating good consistency. Conclusions The detection rate of DCD among preschool children in Wujiang District, Suzhou City, is relatively high. Factors such as gender, parental education level, family annual income, and housing area significantly influence the occurrence of DCD. The constructed nomogram model demonstrates good discrimination and consistency, providing an intuitive tool for predicting the risk of developmental coordination disorder in children.
Key words
developmental coordination disorder /
nomogram /
prediction model /
preschool children
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
References
[1] Deshmukh AA, Sahu V, Deshpande MS. Prevalence of suspected developmental coordination disorder and its association with preterm and low birth weight in 5-10-year old children[J]. Med J Armed Forces India, 2024, 80(2):153-160.
[2] Gras D, Ploix Maes E, Doulazmi M, et al. Developmental coordination disorder subtypes in children: An unsupervised clustering[J]. Dev Med Child Neurol, 2023, 65(10):1332-1342.
[3] You H, Shi J, Huang F, et al. Advances in genetics and epi-genetics of developmental coordination disorder in children[J]. Brain Sci, 2023, 13(6):940-953.
[4] Weber MD, Draghi TTG, Rohr LA, et al. Health-related quality of life in children with developmental coordination disorder: A systematic review[J]. Health Qual Life Outcomes, 2023, 21(1):62-72.
[5] Ito T, Sugiura H, Ito Y, et al. Decreased walking efficiency in elementary school children with developmental coordination disorder trait[J]. Clin Rehabil, 2023, 37(8):1111-1118.
[6] Draghi TTG, Cavalcante Neto JL, Tudella E. Symptoms of anxiety and depression in school children with and without developmental coordination disorder[J]. J Health Psychol, 2021, 26(10):1519-1527.
[7] Van der Veer G, Kamphorst E, Minnaert A, et al. Assessing motor performance in preschool children: The Zurich Neuromotor Assessment-2 and the Movement Assessment Battery for Children-2[J]. Percept Mot Skills, 2021, 128(5):2014-2032.
[8] 耿姗姗, 戴霄天, 王天景, 等. 中文版小龄发育性协调障碍问卷信效度初步研究[J]. 临床儿科杂志, 2020, 38(12):921-924.
Geng SS, Dai XT, Wang TJ, et al. The preliminary study on the reliability and validity of the Chinese version of the Little Developmental Coordination Disorder Questionnaire[J]. J Clin Pediatr, 2020, 38(12):921-924.(in Chinese)
[9] Blank R, Barnett AL, Cairney J, et al. International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder[J]. Dev Med Child Neurol, 2019, 61(3):242-285.
[10] Zaragas H, Fragkomichelaki O, Geitona M, et al. The effects of physical activity in children and adolescents with developmental coordination disorder[J]. Neurol Int, 2023, 15(3):804-820.
[11] Izadi-Najafabadi S, Gunton C, Dureno Z, et al. Effectiveness of cognitive orientation to occupational performance intervention in improving motor skills of children with developmental coordination disorder: A randomized waitlist-control trial[J]. Clin Rehabil, 2022, 36(6):776-788.
[12] Izadi-Najafabadi S, Rinat S, Zwicker JG. Brain functional connectivity in children with developmental coordination disorder following rehabilitation intervention[J]. Pediatr Res, 2022, 91(6):1459-1468.
[13] González López A, Crespo Madrid V, Hidalgo-Robles Á, et al. Early signs of functioning and contextual factors in children 0 to 6 years of age at high risk of or with developmental coordination disorder: A scoping review[J]. Child Care Health Dev, 2023, 49(2):230-239.
[14] Delgado-Lobete L, Montes-Montes R, Pértega-Díaz S, et al. Motor performance and daily participation in children with and without probable developmental coordination disorder[J]. Dev Med Child Neurol, 2022, 64(2):220-227.
[15] 管萍, 章丽丽, 魏艳, 等. 无锡市学龄前儿童发育性运动协调障碍调查[J]. 华南预防医学, 2019, 45(6):533-535.
Guan P, Zhang LL, Wei Y, et al. Investigation on deve-lopmental motor coordination disorders in preschool children in Wuxi City[J]. South China J Prev Med, 2019, 45(6):533-535.(in Chinese)
[16] 朱敏慧, 应雅静, 刘相坤. 学龄前儿童发育性运动协调障碍调查研究及干预效果分析[J]. 全科医学临床与教育, 2022, 20(2):133-137.
Zhu MH, Ying YJ, Liu XK. Investigation on developmental coordination disorder in preschool children and analysis of the intervention effect[J]. Clin Educ Gene Pract, 2022, 20(2):133-137.(in Chinese)
[17] Zoia S, Biancotto M, Caravale B, et al. Early factors associated with risk of developmental coordination disorder in very preterm children: A prospective area-based cohort study in Italy[J]. Paediatr Perinat Epidemiol, 2022, 36(5):683-695.
[18] 王晓芬, 欧光忠, 邱伟毓. 泉州市乡村3~6岁儿童发育性协调障碍现况及影响因素分析[J]. 中国健康教育, 2023, 39(5):468-473.
Wang XF, Ou GZ, Qiu WY. Current status and influencing factors of developmental coordination disorder in 3-6 years old children in rural areas of Quanzhou City[J]. Chin J Health Educ, 2023, 39(5):468-473.(in Chinese)
[19] 刘明霞, 花静, 柯李, 等. 中国儿童发育性协调障碍现况分析[J]. 中华儿科杂志, 2021, 59(11):928-934.
Liu MX, Hua J, Ke L, et al. Analysis of developmental coordination disorder in Chinese children[J]. Chin J Pediatr, 2021, 59(11):928-934.(in Chinese)
[20] 杨慧婷, 王欢. 幼儿发育性协调障碍感觉统合失调与家庭运动环境的相关性[J]. 中国学校卫生, 2020, 41(1):86-89,95.
Yang HT, Wang H. Associations of developmental coordination disorders and sensory integration disorders with fa-mily environment for motor development[J]. Chin J School Health, 2020, 41(1):86-89,95.(in Chinese)