Vitamin D insufficiency and deficiency in children and adolescents with different caregivers in Hainan Province

WANG Chen; WU Weijia; HUANG Chuican; LUO Qing; ZAHNG Chunhui; WANG Ping; WU Shaojing; FAN lichun

doi:10.11852/zgetbjzz2024-0480

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Chinese Journal of Child Health Care ›› 2025, Vol. 33 ›› Issue (8) : 893-896. DOI: 10.11852/zgetbjzz2024-0480

Clinical Research

Vitamin D insufficiency and deficiency in children and adolescents with different caregivers in Hainan Province

WANG Chen¹, WU Weijia^2,3, HUANG Chuican⁴, LUO Qing³, ZAHNG Chunhui², WANG Ping², WU Shaojing⁴, FAN lichun^2,4

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Abstract

Objective To analyze the impact of different primary caregivers on vitamin D insufficiency in children aged 0-18 years, and to provide a basis for family-based prevention and control of vitamin D insufficiency in children and adolescents. Methods A total of 12 630 children and adolescents aged 0 - 18 years from 18 regions in Hainan Province were selected as the study population between January 2021 and March 2022. Investigators used a self-designed questionnaire to collect information on caregivers' age, family type, occupation, and educational level. Fasting venous blood samples were collected from the children, and vitamin D levels were measured using electrochemiluminescence immunoassay. Chi-square tests and Fisher's exact tests were used for univariate analysis, and logistic regression was employed for multivariate analysis. Results The detection rate of vitamin D insufficiency and deficiency among children and adolescents aged 0 - 18 years in Hainan Province was 23.42% (2 958/12 630). Significant differences in vitamin D levels were observed based on the child's gender (χ²=215.284),age (χ²=1 484.55), resident area (χ²=180.202), primary caregiver (χ²=229.889), parental occupation (χ²=53.638,51.606), and educational level (χ²=87.965,91.826)and daily outdoor physical activity (χ²=71.844)(P<0.001). After adjusting for confounding factors, multivariate logistic regression analysis revealed thatchildren with grandparents as main caregivers had a higher risk for vitamin D insufficiency and deficiency in children (OR=1.225, 95%CI: 1.009 - 1.487, P<0.05). Conclusions Different primary caregivers have a significant impact on vitamin D levels in children and adolescents. Greater attention should be paid to the family environment to reduce the occurrence of vitamin D insufficiency and deficiency in this population.

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caregivers / vitamin D / insufficiency / deficiency / family rearing environment / children and adolescents

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WANG Chen, WU Weijia, HUANG Chuican, LUO Qing, ZAHNG Chunhui, WANG Ping, WU Shaojing, FAN lichun. Vitamin D insufficiency and deficiency in children and adolescents with different caregivers in Hainan Province[J]. Chinese Journal of Child Health Care. 2025, 33(8): 893-896 https://doi.org/10.11852/zgetbjzz2024-0480

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