Visualization analysis of international knowledge network mapping of the autismspectrum disorder-gut-brain axis in the last decade based on CiteSpace

TIAN Yanping; LI Wei; LI Qinghong; WU Jiana; LAI Yanmei; JIANG Xue; LYU Zhihai

doi:10.11852/zgetbjzz2024-0438

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Chinese Journal of Child Health Care ›› 2025, Vol. 33 ›› Issue (1) : 103-111. DOI: 10.11852/zgetbjzz2024-0438

Visualization analysis of international knowledge network mapping of the autismspectrum disorder-gut-brain axis in the last decade based on CiteSpace

TIAN Yanping, LI Wei, LI Qinghong, WU Jiana, LAI Yanmei, JIANG Xue, LYU Zhihai

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Abstract

Objective To use CiteSpace visualization mapping software to outline the existing research structure in the international field of autism spectrum disorder(ASD)-gut-brain axis, so as to identify and predict research hotspots and their evolving trends in this area. Methods Using the Web of Science database as the source of literature, documents related to ASD-gut-brain axis published between 2013 and 2023 were recorded. CiteSpace software was used to conduct visual analysis of the related literature records, and to draw and interpret the related knowledge map in terms of countries, institutions, authors, co-citations and keywords. Results The average annual number of foreign publications from 2013 to 2023 was 52.3. The most productive collaborating countries were the United States, China, and Italy. The most productive collaborating institutions included University College Cork in Ireland, the University of California in the USA, and Harvard University in the USA. The most productive research team was represented by the group led by Dinan TG. Hotspot keywords included gut microbiota, irritable bowel syndrome, short-chain fatty acids, sodium butyrate, and akkermansia muciniphila. It was predicted that the mechanism of neurodevelopmental regulation of ASD by gut flora through the gut-brain axis and the study of gut microbiome-targeted therapies for ASD will be the research hotspots in the near future. Conclusions The research field of autism-gut-brain axis, although started late, is developing more rapidly. This paper points out potential collaborative authors and institutions and predicts research hotspots, aiming to provide a reference for related studies in this field.

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autism spectrum disorder / gut-brain axis / microbiota-gut-brain axis / scientific knowledge atlas / CiteSpace / Web of Science / visual analysis

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TIAN Yanping, LI Wei, LI Qinghong, WU Jiana, LAI Yanmei, JIANG Xue, LYU Zhihai. Visualization analysis of international knowledge network mapping of the autismspectrum disorder-gut-brain axis in the last decade based on CiteSpace[J]. Chinese Journal of Child Health Care. 2025, 33(1): 103-111 https://doi.org/10.11852/zgetbjzz2024-0438

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