Systematic review of the prevalence and risk factors of tic disorders in Chinese children

JIANG Yanlin; ZHANG Qiang; ZHAI Rui; PENG Yaqi; TAI Ran; WANG Junhong

doi:10.11852/zgetbjzz2022-1258

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Chinese Journal of Child Health Care ›› 2023, Vol. 31 ›› Issue (6) : 661-667. DOI: 10.11852/zgetbjzz2022-1258

Meta Analysis

Systematic review of the prevalence and risk factors of tic disorders in Chinese children

JIANG Yanlin, ZHANG Qiang, ZHAI Rui, PENG Yaqi, TAI Ran, WANG Junhong

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Objective To systematically retrieved the relevant data and analyze the prevalence and risk factors of tic disorders (TD) in China,in order to provide data reference for further study of TD. Methods A literature search of the CNKI, VIP, SinoMed, WanFang Data, PubMed, Embase and Web of Science databases for relevant observational studies, published from database inception to October 2022, was performed. Literature screening, data extraction and evaluation of risk of bias were independently conducted by two researchers. Data analysis was performed using R software. Results Forty-five studies, including 271 172 children and 10 594 TD children, were included in the Meta-analysis. The overall pooled prevalence of TD in China was 2.68% (95%CI:1.47% - 4.83%). Meta-regression analysis revealed that diagnostic criteria were the main source of study heterogeneity. The pooled prevalence of the TD subgroup, defined according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-Ⅳ), was 1.22% (95%CI:0.79% - 1.86%) and its prevalence in males and females was 1.67% (95%CI:0.91% - 3.04%) and 1.21% (95%CI:0.83% - 1.78%), respectively. Factors associated with TD included preterm birth, abnormal birth weight, neonatal jaundice, other perinatal factors, poor dietary habits, excessive use of electronic devices, history of high fever or febrile convulsions, recurrent respiratory infection, rhinopathy or asthma, attention-deficit hyperactivity disorder or other neurological comorbidities, sleep disorder, family history, psychiatric abnormality during pregnancy, corporal punishment, spoil, single-parent families, emotional lability, and high stress levels. Conclusions The prevalence of TD in China is similar to that in other countries, and males are more prevalent than females. The occurrence of TD is closely related to perinatal factors, chronic respiratory disease, and family stability.

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tic disorders / prevalence rate / risk factor / Meta-analysis

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JIANG Yanlin, ZHANG Qiang, ZHAI Rui, PENG Yaqi, TAI Ran, WANG Junhong. Systematic review of the prevalence and risk factors of tic disorders in Chinese children[J]. Chinese Journal of Child Health Care. 2023, 31(6): 661-667 https://doi.org/10.11852/zgetbjzz2022-1258

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