Associations between breastfeeding and neurodevelopment in infants

CHEN Jia-jie; LIN Li-zi; HUANG Sai-jun; WANG Xin; GUO Cui-hua; WU Ning; JING Jin; CAO Mu-qing

doi:10.11852/zgetbjzz2021-0921

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Chinese Journal of Child Health Care ›› 2021, Vol. 29 ›› Issue (9) : 937-941. DOI: 10.11852/zgetbjzz2021-0921

Original Articles

Associations between breastfeeding and neurodevelopment in infants

CHEN Jia-jie^*, LIN Li-zi, HUANG Sai-jun, WANG Xin, GUO Cui-hua, WU Ning, JING Jin, CAO Mu-qing

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Abstract

Objective To investigate the associations between breastfeeding and neurodevelopment in infants,so as to provide evidence for improving breastfeeding rate. Methods Infants who took regular physical examination from two maternal and child health centers in Guangdong from August to December 2016 were enrolled in this study. Children's basic information and feeding patterns were obtained via questionnaire. Ages and Stages Questionnaire(ASQ) was used to evaluate infants' neurodevelopment. Multiple linear regression and Logistic regression were used to analyze the associations between feeding patterns and neurodevelopment of the included infants. Results Totally 245 infants were included,41.6% of whom was breastfed. The abnormal rate of communication domain was the highest(46.5%) and the gross motor domain was the lowest(16.3%) among all neurodevelopmental domains. After adjusted for potential confounding,children with formula feeding scored lower in communication domain and person-social domain(β=-11.18,95%CI:-18.13 to -4.22,P<0.001; β=-7.61,95%CI:-12.59 to -2.64,P<0.001),and scored higher in social-emotional domain(β=17.78,95%CI: 4.88-30.69,P=0.01) when compared with those of breastfeeding. Formula feeding was a risk factor for delayed development of person-social domain(OR=3.24,95%CI:1.19-9.10,P=0.02) and social-emotional domain(OR=3.39,95%CI:1.34-8.94,P=0.01). Conclusion Breastfeeding,one of the protective factors,is important for the development of person-social and social-emotional domains during infancy.

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breastfeeding / neurodevelopment / infants

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CHEN Jia-jie, LIN Li-zi, HUANG Sai-jun, WANG Xin, GUO Cui-hua, WU Ning, JING Jin, CAO Mu-qing. Associations between breastfeeding and neurodevelopment in infants[J]. Chinese Journal of Child Health Care. 2021, 29(9): 937-941 https://doi.org/10.11852/zgetbjzz2021-0921

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