Dietary zinc intake and serum zinc level and their association with cardiovascular diseases risk factors in children and adolescents

ZHU Qian-rang; DAI Yue; ZHANG Jian; ZHANG Jing-xian; XIE Wei

doi:10.11852/zgetbjzz2021-0703

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Chinese Journal of Child Health Care ›› 2021, Vol. 29 ›› Issue (12) : 1304-1308. DOI: 10.11852/zgetbjzz2021-0703

Dietary zinc intake and serum zinc level and their association with cardiovascular diseases risk factors in children and adolescents

ZHU Qian-rang^*, DAI Yue, ZHANG Jian, ZHANG Jing-xian, XIE Wei

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Abstract

Objective To estimate the level of dietary zinc intake and serum zinc among children and adolescents in Jiangsu province from 2016 to 2017, and to explore the association of dietary zinc intake or serum zinc concentrations with nutrition-related cardiovascular disease risk factors. Methods A total of 1 251 children and adolescents aged from 6 to 17 years were selected from 12 monitoring sites in Jiangsu Province from 2016 to 2017 by multi-stage stratified random sampling.Participants took physical examinations (height, weight, waist circumference), biochemical tests (serum zinc, fasting blood glucose and lipids) and dietary intake assessment (24-hour dietary recall for 3 consecutive days).Pearson χ² test, Kruskal-Wallis test and linear regression model were used to conduct statistical analysis. Results A total of 1 122 children and adolescents aged 6 to 17 years were included in this study.The amount of zinc intake in 39.39% of the participates was below average requirement, whereas it was 56.7% for the participates aged from 13 to 17 and 54.8% for rural participates.The proportion of participants whose serum zinc levels were lower than the reference value was low (0.5%).But there were differences in serum zinc levels among different genders and regions, among which male and urban participants had higher serum zinc levels.Linear regression showed that there was no linear association between dietary zinc intake and serum zinc levels, and there was a weak positive association between dietary zinc intake and high density lipoprotein (β=0.072, 95%CI:0.034 - 0.111, P<0.001) and a negative association between serum zinc and fasting blood glucose(β=-0.506,95%CI:-0.575 - 0.437, P<0.001). Conclusions Children and adolescents in Jiangsu Province are still at a high risk of insufficient dietary zinc intake.Adequate dietary zinc intake and high serum zinc level in children and adolescents are related to good metabolic status.

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zinc / cardiovascular disease / metabolic risk factors / children and adolescents

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ZHU Qian-rang, DAI Yue, ZHANG Jian, ZHANG Jing-xian, XIE Wei. Dietary zinc intake and serum zinc level and their association with cardiovascular diseases risk factors in children and adolescents[J]. Chinese Journal of Child Health Care. 2021, 29(12): 1304-1308 https://doi.org/10.11852/zgetbjzz2021-0703

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