Objective To observe the distribution of difference between bone age and age (BAD) in children at different age stages, and to explore the correlation betweenoverweight and obese children with abnormal bone age development. Methods Totally 21 699 children and adolescents aged 6 to 18 years, who took physical examination in the Affiliated Children's Hospital Capital Institute of Pediatrics from January 2010 to December 2020, were enrolled. The bone age was evaluated by CHN method on left hand radiographs. According to the cut-off point recommended by WHO, the subjects were classified into normal group, overweight and obesity groups. The distribution characteristics of BAD in children with different ages and nutritional status were analyzed. The key time point of bone age advance in overweight and obese children was evaluated. Results The children were mainly school-age children aged 6—12 years, of whom 48.6% were boys and 51.4% were girls. The detection rate of BAD >1 in normal, overweight and obese children was statistically significant (χ2=1 703.70, P<0.05). The average value of BAD in overweight and obese children was higher than that in normal children among most age groups, and the average value of BAD was higher than 1 in 6- to 11-year-old obese boys and 6- to 10-year-old obese girls. There was significant difference in average value of BAD between 6- to 12-year-old boys and 13- to 15-year-old boys in obesity groups (t= 9.47, P<0.05), and the average BAD of 6- to 12-year-old boys was higher than 1. There were significant differences in BAD between girls aged 6 to 12 years and 13 to15 years in overweight and obese group (t=9.695, 13.118, P<0.05), and the average BAD of 6—12 years old girls in overweight and obesity group were higher than 1. Conclusion The BAD of overweight and obese children is significantly obvious than that of normal children, and the BAD of 6- to 12-year-old children is the most obvious. Early bone age has a strong influence on children's normal growth and final height, which should be paid more attention and intervention.
Key words
bone age /
the difference between bone age and age /
overweight and obesity
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